ReviewCellular and molecular life sciences : CMLS2011
Non-conventional sources of peptides presented by MHC class I.
Review in Cellular and molecular life sciences : CMLS, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 67 citations in OpenAlex.
- Review
- Unlocking the secrets of the immunopeptidome: MHC molecules, ncRNA peptides, and vesicles in immune response.Frontiers in immunology · 2025Review
- Untranslated regions (UTRs) are a potential novel source of neoantigens for personalised immunotherapy.Frontiers in immunology · 2024Article
- Article
- The Hidden Enemy Within: Non-canonical Peptides in Virus-Induced Autoimmunity.Frontiers in microbiology · 2022Article
- Understanding small ORF diversity through a comprehensive transcription feature classification.DNA research : an international journal for rapid publication of reports on genes and genomes · 2021Review
- The Neoantigen Landscape of Mycosis Fungoides.Frontiers in immunology · 2020Article
- Nuclear processing of nascent transcripts determines synthesis of full-length proteins and antigenic peptides.Nucleic acids research · 2019Article
- Neoantigens in Hematological Malignancies-Ultimate Targets for Immunotherapy?Frontiers in immunology · 2019Review
- Comprehensive profiling of translation initiation in influenza virus infected cells.PLoS pathogens · 2019Article
- Antisense-Derived HIV-1 Cryptic Epitopes Are Not Major Drivers of Viral Evolution during the Acute Phase of Infection.Journal of virology · 2018Article
- Mining for Micropeptides.Trends in cell biology · 2017Review
- Alternative Start Sites Downstream of Non-Sense Mutations Drive Antigen Presentation and Tolerance Induction to C-Terminal Epitopes.Journal of immunology (Baltimore, Md. : 1950) · 2017Article
- Decoding sORF translation - from small proteins to gene regulation.RNA biology · 2016Review
- Presentation of Cryptic Peptides by MHC Class I Is Enhanced by Inflammatory Stimuli.Journal of immunology (Baltimore, Md. : 1950) · 2016Article
- Nowhere to hide: unconventional translation yields cryptic peptides for immune surveillance.Immunological reviews · 2016Review
- Defining Viral Defective Ribosomal Products: Standard and Alternative Translation Initiation Events Generate a Common Peptide from Influenza A Virus M2 and M1 mRNAs.Journal of immunology (Baltimore, Md. : 1950) · 2016Article
- Translation from the 5' untranslated region shapes the integrated stress response.Science (New York, N.Y.) · 2016Article
- Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames.Nature communications · 2016Article
- Enhanced Recognition of HIV-1 Cryptic Epitopes Restricted by HLA Class I Alleles Associated With a Favorable Clinical Outcome.Journal of acquired immune deficiency syndromes (1999) · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Effectiveness of immune surveillance of intracellular viruses and bacteria depends upon a functioning antigen presentation pathway that allows infected cells to reveal the presence of an intracellular pathogen. The antigen presentation pathway uses virtually all endogenous polypeptides as a source to produce antigenic peptides that are eventually chaperoned to the cell surface by MHC class I molecules. Intriguingly, MHC I molecules present peptides encoded not only in the primary open reading frames but also those encoded in alternate reading frames. Here, we review recent studies on the generation of cryptic pMHC I. We focus on the immunological significance of cryptic pMHC I, and the novel translational mechanisms that allow production of these antigenic peptides from unconventional sources.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.