Evidence map›Paper›PMID 21390485›Full record

ArticleMolecular biotechnology2011

Development of a flow-through [corrected] microarray based reverse transcriptase multiplex ligation-dependent probe amplification assay for the detection of European Bunyaviruses. [corrected].

Lekbira Hasib, Meik Dilcher, Frank Hufert, Ursula Meyer-König, Ursula König-Meyer, Manfred Weidmann

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Molecular biotechnology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. An Assay for Variable Fragment Length Allele-Specific Genotyping.Methods in molecular biology (Clifton, N.J.) · 2025
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4 · The record

Corrections and comments

  • Erratum issued
    König-Meyer, Ursula [corrected to Meyer-König, Ursula]
5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lekbira HasibDepartment of Virology, University Medical Center Göttingen, Kreuzbergring 57 37075, Göttingen, Germany. lhasib@gwdg.de
Meik Dilcher
Frank Hufert
Ursula Meyer-König
Ursula König-Meyer
Manfred Weidmann
Universitätsmedizin Göttingen · DEUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is suspected that apart from tick-borne encephalitis virus several additional European Arboviruses such as the sandfly borne Toscana virus, sandfly fever Sicilian virus and sandfly fever Naples virus, mosquito-borne Tahyna virus, Inkoo virus, Batai virus and tick-borne Uukuniemi virus cause aseptic meningo-encephalitis or febrile disease in Europe. Currently, the microarray technology is developing rapidly and there are many efforts to apply it to infectious diseases diagnostics. In order to arrive at an assay system useful for high throughput analysis of samples from aseptic meningo-encephalitis cases the authors developed a combined multiplex ligation-dependent probe amplification and flow-through microarray assay for the detection of European Bunyaviruses. These results show that this combined assay indeed is highly sensitive, and specific for the accurate detection of multiple viruses.

Indexed as

AnimalsArbovirusesChlorocebus aethiopsEuropeNucleic Acid Amplification TechniquesNucleic Acid HybridizationOligonucleotide Array Sequence AnalysisOligonucleotidesOrthobunyavirusPhlebovirusRNA-Directed DNA PolymeraseRNA, ViralSensitivity and SpecificityTemperatureVero CellsOligonucleotidesRNA-Directed DNA PolymeraseRNA, Viral

Identifiers

PMID21390485
PMCPMC3172416
OpenAlexW2020019095

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.