Evidence map›Paper›PMID 21390438›Full record

ReviewJornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia

Myositis-related interstitial lung disease and antisynthetase syndrome.

Joshua Solomon, Jeffrey J Swigris, Kevin K Brown

Open access · diamondAbstract readReview
In one paragraph

Review in Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 169 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
169citing papers in PubMed, 4 pooled it
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

169 citing papers in PubMed, 4 syntheses or guidelines pooled it, 317 citations in OpenAlex.

  1. Pooled it
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  3. Defining anti-synthetase syndrome: a systematic literature review.Clinical and experimental rheumatology · 2022
    Pooled it
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109 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Joshua SolomonInterstitial Lung Disease Program, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, USA. solomonj@njhealth.org
Jeffrey J Swigris
Kevin K Brown
University of Colorado Denver · USNational Jewish Health · US

Funding

Pulmonary Rehabilitation for Idiopathic Pulmonary FibrosisK23HL092227 · NHLBI · NATIONAL JEWISH HEALTH · PI SWIGRIS, JEFFREY J · 2009 to 2013
$657k
NHLBI NIH HHS K23 HL092227
6 · The paper itself

Abstract

In patients with myositis, the lung is commonly involved, and the presence of anti-aminoacyl-tRNA synthetase (anti-ARS) antibodies marks the presence or predicts the development of interstitial lung disease (ILD). A distinct clinical entity-antisynthetase syndrome-is characterized by the presence of anti-ARS antibodies, myositis, ILD, fever, arthritis, Raynaud's phenomenon, and mechanic's hands. The most common anti-ARS antibody is anti-Jo-1. More recently described anti-ARS antibodies might confer a phenotype that is distinct from that of anti-Jo-1-positive patients and is characterized by a lower incidence of myositis and a higher incidence of ILD. Among patients with antisynthetase syndrome-related ILD, the response to immunosuppressive medications is generally, but not universally, favorable.

Indexed as

Amino Acyl-tRNA SynthetasesAntibodies, AntinuclearAntigens, Human PlateletAutoantibodiesHumansLung Diseases, InterstitialMyositisAmino Acyl-tRNA SynthetasesAntibodies, AntinuclearAntigens, Human PlateletAutoantibodiesJo-1 antibody

Identifiers

PMID21390438
PMCPMC3676869
OpenAlexW2004089161

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.