Evidence map›Paper›PMID 21389976›Full record

ReviewKidney international2011

Non-pharmacological aspects of blood pressure management: what are the data?

S Susan Hedayati, Essam F Elsayed, Robert F Reilly

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Kidney international, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04099550 (Effect of Real-time Continuous Glucose Monitoring System in Overweight or Obese Adults With Prediabetes), which is not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04099550 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Effect of Real-time Continuous Glucose Monitoring System in Overweight or Obese Adults With Prediabetes

TypeinterventionalSponsorPusan National University HospitalRan2019 to 2021Enrolled30ConditionsContinuous Glucose Monitoring, Prediabetic State, ObesityArmsRT-CGM, SMBG
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 56 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Food as Medicine for Hypertension: Microbiota as Mediators.Hypertension (Dallas, Tex. : 1979) · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. The role of angiotensin II in nonalcoholic steatohepatitis.Molecular and cellular endocrinology · 2013
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

S Susan HedayatiRenal Section, Medical Service, Veterans Affairs North Texas Health Care System, Dallas, Texas 75216-7167, USA. susan.hedayati@utsouthwestern.edu
Essam F Elsayed
Robert F Reilly
The University of Texas Southwestern Medical Center · USVA North Texas Health Care System · US

Funding

UT Southwestern O'Brien Kidney Research Core CenterP30DK079328 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI MOE, ORSON W · 2007 to 2021
$16.9M
NIDDK NIH HHS P30 DK079328NIDDK NIH HHS P30DK079328
6 · The paper itself

Abstract

Hypertension affects 29% of US adults and is a significant risk factor for cardiovascular morbidity and mortality. Epidemiological data support contribution of several dietary and other lifestyle-related factors to the development of high blood pressure (BP). Several clinical trials investigated the efficacy of non-pharmacological interventions and lifestyle modifications to reduce BP. Best evidence from randomized controlled trials supports BP-lowering effects of weight loss, the Dietary Approaches to Stop Hypertension (DASH) diet, and dietary sodium (Na(+)) reduction in those with prehypertension, with more pronounced effects in those with hypertension. In hypertensive participants, the effects on BP of DASH combined with low Na(+) alone or with the addition of weight loss were greater than or equal to those of single-drug therapy. Trials where food was provided to participants were more successful in showing a BP-lowering effect. However, clinical studies with long-term follow-up revealed that lifestyle modifications were difficult to maintain. Findings from controlled trials of increased potassium, calcium, or magnesium intake, or reduction in alcohol intake revealed modest BP-lowering effects and are less conclusive. The reported effects of exercise independent of weight loss on BP are inconsistent.

Indexed as

Alcohol DrinkingCalcium, DietaryClinical Trials as TopicDietDiet, Sodium-RestrictedExerciseHumansHypertensionMagnesiumPotassium, DietaryWeight LossCalcium, DietaryMagnesiumPotassium, Dietary

Identifiers

PMID21389976
PMCPMC3226743
OpenAlexW2083644515

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.