Evidence map›Paper›PMID 21386976›Full record

ArticleClinical epidemiology2011

The worldwide epidemiology of acute rheumatic fever and rheumatic heart disease.

Michael D Seckeler, Tracey R Hoke

2 registry-linked trialsAbstract read
In one paragraph

Article in Clinical epidemiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 170 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
170citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01550068 nacompletednot on this mapstarted 2012, after this paper: background citation

A Population-Based Study of Prevalence of Rheumatic Heart Disease and Cardiovascular Outcomes Among Schoolchildren in Nepal

TypeinterventionalSponsorInsel Gruppe AG, University Hospital BernRan2012 to 2019Enrolled8,519ConditionsRheumatic Heart DiseaseArmsEchocardiography
NCT06054568 unknown statusnot on this mapstarted 2023, after this paper: background citation

Ventricular-arterial Coupling of the Heart Among Patients With Mitral Stenosis Undergoing Percutaneous Trans-luminal Mitral Commissurotomy. Cardiac Magnetic Resonance Study

TypeobservationalSponsorAssiut UniversityRan2023 to 2026Enrolled46ConditionsMitral Valve Stenosis
3 · Its place in the literature

Who cites it

170 citing papers in PubMed, 10 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Predictors of rheumatic fever in sore throat patients: a systematic review and meta-analysis.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2022
    Pooled it
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  10. Guideline
  11. Trial
  12. Article
  13. Immune Mechanisms of Heart Valve Development, Homeostasis, and Disease.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
  14. The global burden of rheumatic heart disease: 1990-2021.Clinical medicine (London, England) · 2026
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

110 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael D SeckelerDepartment of Pediatrics, Division of Cardiology, University of Virginia, Charlottesville, VA, USA.
Tracey R Hoke

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are significant public health concerns around the world. Despite decreasing incidence, there is still a significant disease burden, especially in developing nations. This review provides background on the history of ARF, its pathology and treatment, and the current reported worldwide incidence of ARF and prevalence of RHD.

Indexed as

epidemiologygroup A streptococcusrheumatic feverrheumatic heart disease

Identifiers

PMID21386976
PMCPMC3046187

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.