ReviewNature reviews. Neurology2011
Differentiating between nonepileptic and epileptic seizures.
Review in Nature reviews. Neurology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 57 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ketogenic Diet Effects on the Frequency of Non Epileptic Seizures in Patients With Dissociative Neurological Symptom Disorder: a Pilot Study
Accelerated, Left Prefrontal Transcranial Magnetic Stimulation for Functional Seizures; An Open-Label Exploration of Feasibility, Tolerability, and Preliminary Efficacy
Who cites it
57 citing papers in PubMed, 1 synthesis or guideline pooled it, 191 citations in OpenAlex.
- Recommendations for the community-based management of prolonged convulsive seizures in children in Europe.BMC pediatrics · 2026Guideline
- Protocol on transcranial alternating current stimulation for the treatment of major depressive disorder: a randomized controlled trial.Chinese medical journal · 2020Trial
- Artificial Intelligence for Improving the Management of People With Epilepsy in Low-and-Middle Income Countries.European journal of neurology · 2026Review
- When Mind Hurts the Skin: A Rare Case of Dermatitis Artefacta in an Epileptic Female.Clinical case reports · 2026Article
- Semiological differences of functional seizures between pediatrics and adults: video electroencephalography analysis.Acta epileptologica · 2026Article
- Primum non nocere: Endotracheal Intubation for Prolonged Functional/Dissociative Seizures in an Adolescent.Journal of Brown hospital medicine · 2025Article
- Brain network entropy, depression, and quality of life in people with traumatic brain injury and seizure disorders.Epilepsia open · 2024Article
- Benzodiazepine receipt in adults with psychogenic non-epileptic seizures in the USA.BMJ neurology open · 2024Article
- New insights on the potential anti-epileptic effect of metformin: Mechanistic pathway.Journal of cellular and molecular medicine · 2023Review
- The standardized extract of Centella asiatica L. Urb attenuates the convulsant effect induced by lithium/pilocarpine without affecting biochemical and haematological parameters in rats.BMC complementary medicine and therapies · 2023Article
- Cushing's Disease Presenting with Functional Neurological (Conversion) Disorder.Case reports in psychiatry · 2023Article
- Clinical Functional Seizure Score (CFSS): a simple algorithm for clinicians to suspect functional seizures.Frontiers in neurology · 2023Article
- Socioemotional self- and co-regulation in functional seizures: comparing high and low posttraumatic stress.Frontiers in psychiatry · 2023Article
- Seizures in adults with suspected central nervous system infection.BMC neurology · 2022Article
- Teaching distinguishing semiological features improves diagnostic accuracy of seizure-like events by emergency physicians.Neurological research and practice · 2022Article
- Remote Patient Monitoring for Neuropsychiatric Disorders: A Scoping Review of Current Trends and Future Perspectives from Recent Publications and Upcoming Clinical Trials.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2022Article
- Using Semiology to Classify Epileptic Seizures vs Psychogenic Nonepileptic Seizures: A Meta-analysis.Neurology. Clinical practice · 2022Article
- Neurology residents' education in functional seizures.Epilepsy & behavior reports · 2022Article
- Functional seizures: The patient's perspective of a diagnostic and treatment odyssey.Epilepsy & behavior reports · 2022Article
- A Machine Learning Approach Involving Functional Connectivity Features to Classify Rest-EEG Psychogenic Non-Epileptic Seizures from Healthy Controls.Sensors (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Psychogenic nonepileptic seizures (PNES) resemble epileptic seizures and are often misdiagnosed and mistreated as the latter. Occasionally, epileptic seizures are misdiagnosed and mistreated as PNES. 70% of PNES cases develop between the second and fourth decades of life, but this disease can also affect children and the elderly. At least 10% of patients with PNES have concurrent epileptic seizures or have had epileptic seizures before being diagnosed with PNES. Psychological stress exceeding an individual's coping capacity often precedes PNES. Clinicians can find differentiating between PNES and epileptic seizures challenging. Some clinical features can help distinguish PNES from epileptic seizures, but other features associated with PNES are nonspecific and occur during both types of seizures. Diagnostic errors often result from an overreliance on specific clinical features. Note that no single feature is pathognomonic for PNES. When typical seizures can be recorded, video-EEG is the diagnostic gold standard for PNES, and in such cases a diagnosis can be made with high accuracy. When video-EEG reveals no epileptiform activity before, during or after the ictus, thorough neurological and psychiatric histories can be used to confirm the diagnosis of PNES. In this article, we review the clinical features that can help clinicians differentiate between PNES and epileptic seizures.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.