ArticleQJM : monthly journal of the Association of Physicians2011
Fracture incidence after liver transplantation: results of a 10-year audit.
Article in QJM : monthly journal of the Association of Physicians, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 26 citations in OpenAlex.
- Vertebral fracture incidence and risk factors following liver transplantation: tertiary transplant center experience.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Results of the implementation of a multidisciplinary care protocol for preventing fragility fractures following liver transplantation.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Article
- The Incidence and Risk Factors of Hip Fracture after Liver Transplantation (LT): A Nationwide Population-Based Study.BioMed research international · 2019Article
- Bone metabolism dynamics in the early post-transplant period following kidney and liver transplantation.PloS one · 2018Article
- The impact of osteoporosis on health-related quality of life in patients after liver transplantation - a pilot study.Przeglad gastroenterologiczny · 2015Article
- Caring for the Bone Health Among Liver Transplant Recipients.Journal of clinical and experimental hepatologyReview
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHigh rates of fracture following liver transplantation were reported in earlier years, but the impact of subsequent changes in immune suppression and the introduction of bone-protective therapy on fracture rate have not been reported.
aimThe aim of this study was to document clinical fracture incidence during the period 1998-2008 in a single transplant centre, following the introduction of a bone management protocol.
designIt was designed as a retrospective cohort.
methodsRecords were retrieved from 531 of 592 eligible patients in an audit of all patients undergoing a first liver transplant during the 10-year period. All fractures were verified radiologically.
resultsThe mean follow-up period was 61.4 months. Prior to transplantation 5.6% of patients had a history of fracture. Incident clinical fractures following transplantation were recorded in just 15 (3.5%) patients. The most common fracture site was the spine and the median time from transplant to fracture was 26 months (range 2-83 months).
conclusionThere was a low fracture rate in patients undergoing liver transplantation in this centre over the past 10 years. This rate is lower than that in previous reports, which is likely to reflect the use of lower doses of prednisolone for immune suppression and the administration of bone-protective therapy to high-risk patients.
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