ArticleVirology journal2011
The preparation of an infectious full-length cDNA clone of Saffold virus.
Article in Virology journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 26 citations in OpenAlex.
- Saffold virus exploits integrin αvβ8 and sulfated glycosaminoglycans as cooperative attachment receptors for infection.Nature communications · 2025Article
- Generation of a recombinant Saffold Virus expressing UnaG as a marker for the visualization of viral infection.Virology journal · 2023Article
- Viruses in Vietnamese Patients Presenting with Community-Acquired Sepsis of Unknown Cause.Journal of clinical microbiology · 2019Article
- Frequent detection of Saffold cardiovirus in adenoids.PloS one · 2019Article
- Saffold virus, an emerging human cardiovirus.Reviews in medical virology · 2017Review
- Intracerebral Inoculation of Mouse-Passaged Saffold Virus Type 3 Affects Cerebellar Development in Neonatal Mice.Journal of virology · 2016Article
- Structure and Genome Release Mechanism of the Human Cardiovirus Saffold Virus 3.Journal of virology · 2016Article
- The Pathogenesis of Saffold Virus in AG129 Mice and the Effects of Its Truncated L Protein in the Central Nervous System.Viruses · 2016Article
- Article
- Establishment of a panel of in-house polyclonal antibodies for the diagnosis of enterovirus infections.Neuropathology : official journal of the Japanese Society of Neuropathology · 2015Article
- Prevalence and genetic characteristics of Saffold cardiovirus in China from 2009 to 2012.Scientific reports · 2015Article
- Saffold Virus, a Human Cardiovirus, and Risk of Persistent Islet Autoantibodies in the Longitudinal Birth Cohort Study MIDIA.PloS one · 2015Article
- Saffold virus is able to productively infect primate and rodent cell lines and induces apoptosis in these cells.Emerging microbes & infections · 2014Article
- Saffold virus type 3 (SAFV-3) persists in HeLa cells.PloS one · 2013Article
- A newly designed real-time RT-PCR for SAFV detects SAFV-2 and SAFV-3 in the respiratory tracts of ill children during 2011.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2012Article
- Saffold virus, a novel human Cardiovirus with unknown pathogenicity.Journal of virology · 2012Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The pathogenicity of Saffold virus (SAFV) among humans still remains unclear, although it was identified as a novel human cardiovirus in 2007. In order to encourage the molecular pathogenetic studies of SAFV, we generated an infectious cDNA clone of SAFV type 3 (SAFV-3). The present study demonstrated that the synthesis of the full-length infectious RNA by T7 RNA polymerase was terminated by a homologous sequence motif with the human preproparathyroid hormone (PTH) signal in the SAFV-3 genome. To obtain the infectious RNA using T7 promoter, a variant of T7 RNA polymerase, which fails to recognize the PTH signal, was useful. This study will provide a valuable technical insight into the reverse genetics of SAFV.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.