Evidence map›Paper›PMID 21384252›Full record

ReviewJournal of assisted reproduction and genetics2011

Advancements in reprogramming strategies for the generation of induced pluripotent stem cells.

Mei I Lai, Wai Yeng Wendy-Yeo, Rajesh Ramasamy, Norshariza Nordin, Rozita Rosli, Abhi Veerakumarasivam, Syahril Abdullah

Abstract readReview
In one paragraph

Review in Journal of assisted reproduction and genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Urine-derived cells for human cell therapy.Stem cell research & therapy · 2018
    Review
  6. Generation of defined neural populations from pluripotent stem cells.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018
    Review
  7. Article
  8. Modeling AEC-New approaches to study rare genetic disorders.American journal of medical genetics. Part A · 2014
    Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mei I LaiDepartment of Pathology, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, 43400, Serdang UPM, Selangor, Malaysia.
Wai Yeng Wendy-Yeo
Rajesh Ramasamy
Norshariza Nordin
Rozita Rosli
Abhi Veerakumarasivam
Syahril Abdullah

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Direct reprogramming of somatic cells into induced pluripotent stem (iPS) cells has emerged as an invaluable method for generating patient-specific stem cells of any lineage without the use of embryonic materials. Following the first reported generation of iPS cells from murine fibroblasts using retroviral transduction of a defined set of transcription factors, various new strategies have been developed to improve and refine the reprogramming technology. Recent developments provide optimism that the generation of safe iPS cells without any genomic modification could be derived in the near future for the use in clinical settings. This review summarizes current and evolving strategies in the generation of iPS cells, including types of somatic cells for reprogramming, variations of reprogramming genes, reprogramming methods, and how the advancement iPS cells technology can lead to the future success of reproductive medicine.

Indexed as

Gene RearrangementAnimalsCell Culture TechniquesCell DifferentiationCloning, MolecularFibroblastsGenetic VectorsGene Transfer TechniquesHumansInduced Pluripotent Stem CellsMiceMicroRNAsPlasmidsReproductive TechniquesRetroviridaeTranscription FactorsMicroRNAsTranscription Factors

Identifiers

PMID21384252
PMCPMC3114956

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.