Evidence map›Paper›PMID 21383971›Full record

ReviewPLoS pathogens2011

A fresh look at the origin of Plasmodium falciparum, the most malignant malaria agent.

Franck Prugnolle, Patrick Durand, Benjamin Ollomo, Linda Duval, Frédéric Ariey, Céline Arnathau, Jean-Paul Gonzalez, Eric Leroy, François Renaud

Abstract readReview
In one paragraph

Review in PLoS pathogens, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Overview ofComparative medicine · 2024
    Review
  8. Article
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  11. Article
  12. Article
  13. Review
  14. Molecular Identification ofPathogens (Basel, Switzerland) · 2021
    Article
  15. Article
  16. An unexpected diversity of trypanosomatids in fecal samples of great apes.International journal for parasitology. Parasites and wildlife · 2018
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Franck PrugnolleLaboratoire MIVEGEC (UM1-CNRS-IRD), Montpellier, France. franck.prugnolle@ird.fr
Patrick Durand
Benjamin Ollomo
Linda Duval
Frédéric Ariey
Céline Arnathau
Jean-Paul Gonzalez
Eric Leroy
François Renaud

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

From which host did the most malignant human malaria come: birds, primates, or rodents? When did the transfer occur? Over the last half century, these have been some of the questions up for debate about the origin of Plasmodium falciparum, the most common and deadliest human malaria parasite, which is responsible for at least one million deaths every year. Recent findings bring elements in favor of a transfer from great apes, but are these evidences really solid? What are the grey areas that remain to be clarified? Here, we examine in depth these new elements and discuss how they modify our perception of the origin and evolution of P. falciparum. We also discuss the perspectives these new discoveries open.

Indexed as

Biological EvolutionAnimalsAnimals, WildHumansMalaria, FalciparumPan troglodytesPhylogenyPlasmodium falciparumProtozoan Infections, AnimalZoonoses

Identifiers

PMID21383971
PMCPMC3044689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.