ArticleAntimicrobial agents and chemotherapy2011
PER-7, an extended-spectrum beta-lactamase with increased activity toward broad-spectrum cephalosporins in Acinetobacter baumannii.
Article in Antimicrobial agents and chemotherapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 56 citations in OpenAlex.
- Comparative activity of sulbactam and sulbactam/durlobactam against carbapenem-resistant A. baumannii isolates producing OXA-23 or OXA-23 plus PER-1 enzymes.The Journal of antibiotics · 2026Article
- Development of a Multiplex PCR Assay for the Detection of Extended-Spectrum Beta-Lactamase Genes inIndian journal of microbiology · 2024Article
- First Report of Complete Genome Analysis of Multiple Drug ResistanceTransboundary and emerging diseases · 2024Article
- Genomic epidemiology reveals multidrug resistant plasmid spread between Vibrio cholerae lineages in Yemen.Nature microbiology · 2023Article
- Extended-spectrum β-lactamases: an update on their characteristics, epidemiology and detection.JAC-antimicrobial resistance · 2021Review
- Diversity of International High-Risk Clones ofAntibiotics (Basel, Switzerland) · 2021Article
- Review
- Genomic and Phenotypic Analysis of Multidrug-ResistantPathogens (Basel, Switzerland) · 2021Article
- Molecular characterization of carbapenem-resistant Acinetobacter baumannii clinical isolates from Egyptian patients.PloS one · 2021Article
- Antibiotic Resistance Profiles, Molecular Mechanisms and Innovative Treatment Strategies ofMicroorganisms · 2020Review
- Prevalence of extended-spectrum beta-lactamase genes in Acinetobacter baumannii strains isolated from nosocomial infections in Tehran, Iran.GMS hygiene and infection control · 2019Article
- Antimicrobial Resistance inMicrobiology spectrum · 2018Review
- Transposition of TnAntimicrobial agents and chemotherapy · 2018Article
- PER-8, a Novel Extended-Spectrum β-Lactamase PER Variant, from an Acinetobacter baumannii Clinical Isolate in Nepal.Antimicrobial agents and chemotherapy · 2017Article
- Biology ofFrontiers in cellular and infection microbiology · 2017Review
- Prevalence of carbapenemases among high-level aminoglycoside-resistantExperimental and therapeutic medicine · 2016Article
- Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates.Antimicrobial agents and chemotherapy · 2016Article
- Molecular characterization of ISCR1-mediated blaPER-1 in a non-O1, non-O139 Vibrio cholerae strain from China.Antimicrobial agents and chemotherapy · 2015Article
- Complete nucleotide sequence of a conjugative plasmid carrying bla(PER-1).Antimicrobial agents and chemotherapy · 2015Article
- Wide distribution of carbapenem resistant Acinetobacter baumannii in burns patients in Iran.Frontiers in microbiology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acinetobacter baumannii isolate AP2 was recovered from a bronchial lavage sample of a patient hospitalized in Paris, France. A. baumannii AP2 was resistant to all β-lactams, including carbapenems, and expressed the extended-spectrum β-lactamase (ESBL) PER-7, which differs from PER-1 by 4 amino acid substitutions. Compared to PER-1, PER-7 possessed higher-level hydrolytic activities against cephalosporins and aztreonam. The blaPER-7 gene was chromosomally located and associated with a mosaic class 1 integron structure. Additionally, isolate AP2 expressed the carbapenem-hydrolyzing oxacillinase OXA-23 and the 16S RNA methylase ArmA, conferring high-level resistance to aminoglycosides.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.