Evidence map›Paper›PMID 21383074›Full record

ReviewThe Journal of cell biology2011

On emerging nuclear order.

Indika Rajapakse, Mark Groudine

Abstract readReview
In one paragraph

Review in The Journal of cell biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed.

  1. Epigenetic analyses in forensic medicine: future and challenges.International journal of legal medicine · 2024
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Understanding the 3D genome: Emerging impacts on human disease.Seminars in cell & developmental biology · 2019
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Emergence of function from coordinated cells in a tissue.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  19. Symmetry from Asymmetry or Asymmetry from Symmetry?Cold Spring Harbor symposia on quantitative biology · 2017
    Article
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Indika RajapakseDivision of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Mark Groudine

Funding

MAINTENANCE OF GENE EXPRESSION IN THE RED CELL LINEAGER01HL065440 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI GROUDINE, MARK T · 2000 to 2018
$12.4M
FUNCTION OF HUMAN &MOUSE B GLOBIN LOCUS CONTROL REGIONSR37DK044746 · NIDDK · FRED HUTCHINSON CANCER RESEARCH CENTER · PI GROUDINE, MARK T · 1997 to 2016
$12.3M
Quantitative models and methods for genetic organizationK25DK082791 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RAJAPAKSE, INDIKA · 2009 to 2013
$662k
NHLBI NIH HHS R01 HL065440NHLBI NIH HHS R01 HL65440NIDDK NIH HHS K25 DK082791NIDDK NIH HHS K25DK082791-01A109NIDDK NIH HHS R37 DK044746NIDDK NIH HHS R37 DK44746
6 · The paper itself

Abstract

Although the nonrandom nature of interphase chromosome arrangement is widely accepted, how nuclear organization relates to genomic function remains unclear. Nuclear subcompartments may play a role by offering rich microenvironments that regulate chromatin state and ensure optimal transcriptional efficiency. Technological advances now provide genome-wide and four-dimensional analyses, permitting global characterizations of nuclear order. These approaches will help uncover how seemingly separate nuclear processes may be coupled and aid in the effort to understand the role of nuclear organization in development and disease.

Indexed as

Gene Expression RegulationAnimalsCell NucleusChromatin Assembly and DisassemblyChromosomesGene Regulatory NetworksHumansInterphaseIntranuclear SpaceModels, GeneticNeoplasmsTranslocation, Genetic

Identifiers

PMID21383074
PMCPMC3051810

What OpenQuestion holds

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LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.