ReviewRespiratory physiology & neurobiology2011
Development of synaptic transmission to respiratory motoneurons.
Review in Respiratory physiology & neurobiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 21 citations in OpenAlex.
- Genome-wide DNA methylation analysis of pulmonary function in middle and old-aged Chinese monozygotic twins.Respiratory research · 2021Article
- Development of γ-aminobutyric acid-, glycine-, and glutamate-immunopositive boutons on the rat genioglossal motoneurons.Brain structure & function · 2021Article
- The dorsal and the ventral side of hypoglossal motor nucleus showed different response to chronic intermittent hypoxia in rats.Sleep & breathing = Schlaf & Atmung · 2021Article
- Developmental nicotine exposure disrupts dendritic arborization patterns of hypoglossal motoneurons in the neonatal rat.Developmental neurobiology · 2016Article
- Polyamines as Snake Toxins and Their Probable Pharmacological Functions in Envenomation.Toxins · 2016Article
- Developmental changes in the morphology of mouse hypoglossal motor neurons.Brain structure & function · 2016Article
- Emerging Roles of Filopodia and Dendritic Spines in Motoneuron Plasticity during Development and Disease.Neural plasticity · 2016Review
- Pre- and postsynaptic modulations of hypoglossal motoneurons by α-adrenoceptor activation in wild-type and Mecp2(-/Y) mice.American journal of physiology. Cell physiology · 2013Article
- Respiratory muscles and motoneurons.Respiratory physiology & neurobiology · 2011Article
- Article
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Respiratory motoneurons provide the exclusive drive to respiratory muscles and therefore are a key relay between brainstem neural circuits that generate respiratory rhythm and respiratory muscles that control moment of gases into and out of the airways and lungs. This review is focused on postnatal development of fast ionotropic synaptic transmission to respiratory motoneurons, with a focus on hypoglossal motoneurons (HMs). Glutamatergic synaptic transmission to HMs involves activation of both non-NMDA and NMDA receptors and during the postnatal period co-activation of these receptors located at the same synapse may occur. Further, the relative role of each receptor type in inspiratory-phase motoneuron depolarization is dependent on the type of preparation used (in vitro versus in vivo; neonatal versus adult). Respiratory motoneurons receive both glycinergic and GABAergic inhibitory synaptic inputs. During inspiration phrenic and HMs receive concurrent excitatory and inhibitory synaptic inputs. During postnatal development in HMs GABAergic and glycinergic synaptic inputs have slow kinetics and are depolarizing and with postnatal development they become faster and hyperpolarizing. Additionally shunting inhibition may play an important role in synaptic processing by respiratory motoneurons.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.