ArticleJournal of endourology2011
Factors related to colonization with Oxalobacter formigenes in U.S. adults.
Article in Journal of endourology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed.
- Plasma oxalate and eGFR are correlated in primary hyperoxaluria patients with maintained kidney function-data from three placebo-controlled studies.Pediatric nephrology (Berlin, Germany) · 2021Trial
- A randomised Phase II/III study to evaluate the efficacy and safety of orally administered Oxalobacter formigenes to treat primary hyperoxaluria.Urolithiasis · 2018Trial
- A randomised Phase I/II trial to evaluate the efficacy and safety of orally administered Oxalobacter formigenes to treat primary hyperoxaluria.Pediatric nephrology (Berlin, Germany) · 2017Trial
- Oral antibiotic treatment of Helicobacter pylori leads to persistently reduced intestinal colonization rates with Oxalobacter formigenes.Journal of endourology · 2011Trial
- The effects of antibiotics use during early life and genetic risk on urolithiasis incidence: a large-scale UK biobank cohort study.World journal of urology · 2025Article
- Factors Influencing Oxalate Synthesis in Healthy Volunteers.Journal of endourology · 2025Article
- InducingKidney international reports · 2025Article
- Oxalate Nephropathy and the Mechanism of Oxalate-Induced Kidney Injury.Kidney diseases (Basel, Switzerland) · 2023Review
- Mechanisms of the intestinal and urinary microbiome in kidney stone disease.Nature reviews. Urology · 2022Review
- Dietary Management of Chronic Kidney Disease and Secondary Hyperoxaluria in Patients with Short Bowel Syndrome and Type 3 Intestinal Failure.Nutrients · 2022Review
- Forty Years of Oxalobacter formigenes, a Gutsy Oxalate-Degrading Specialist.Applied and environmental microbiology · 2021Review
- Effect of antibiotic treatment on Oxalobacter formigenes colonization of the gut microbiome and urinary oxalate excretion.Scientific reports · 2021Article
- Article
- Alterations in the gut bacterial microbiome in people with type 2 diabetes mellitus and diabetic retinopathy.Scientific reports · 2021Observational
- The relationship between calcium oxalate lithiasis and chronic proinflammatory intestinal dysbiosis pattern: a prospective study.Urolithiasis · 2020Article
- The gut microbiota and its relationship with chronic kidney disease.International urology and nephrology · 2019Review
- Development of a Humanized Murine Model for the Study of Oxalobacter formigenes Intestinal Colonization.The Journal of infectious diseases · 2019Article
- The use of antibiotics and risk of kidney stones.Current opinion in nephrology and hypertension · 2019Review
- Inhibition of urinary stone disease by a multi-species bacterial network ensures healthy oxalate homeostasis.Kidney international · 2019Article
- Compliance in patients with dietary hyperoxaluria: A cohort study and systematic review.Asian journal of urology · 2019Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
goalsTo elucidate the determinants of Oxalobacter formigenes colonization in humans.
backgroundO. formigenes is a gram-negative anaerobic bacterium that colonizes the colon of a substantial proportion of the normal population and metabolizes dietary and endogenous oxalate. The bacterium has been associated with a large reduction in the odds of recurrent calcium oxalate kidney stones. Subjects were 240 healthy individuals from Massachusetts and North Carolina. O. formigenes was detected by culture of fecal swabs. Information on factors of interest was obtained by telephone interviews and self-administered questionnaires. STUDY
resultsThe overall prevalence of O. formigenes was 38%. Use of specific antibiotics previously thought to affect the bacterium was significantly related to colonization, with prevalences of 17%, 27%, and 36%, for those who had used these drugs <1, 1-5, and >5 years ago, compared with 55% in nonusers. There were no significant associations with demographic factors, nutrient intake, or medical history, although the prevalence appeared to increase somewhat with increasing oxalate consumption.
conclusionsSome antibiotics markedly affect colonization with O. formigenes. Although no other factor was identified as having a material influence on the prevalence of the bacterium, there is much to learn about how an individual acquires the organism and which factors affect persistence of colonization.
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