Evidence map›Paper›PMID 21380944›Full record

ReviewClinical reviews in allergy & immunology2013

Cutting edge issues in the Churg-Strauss syndrome.

Wojciech Szczeklik, Bogdan Jakieła, Dariusz Adamek, Jacek Musiał

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Clinical reviews in allergy & immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. The challenge of treating orphan disease.Clinical reviews in allergy & immunology · 2014
    Article
  4. Autoimmunity in 2013.Clinical reviews in allergy & immunology · 2014
    Review
  5. Clinical features and prognostic factors of Churg-Strauss syndrome.The Korean journal of internal medicine · 2014
    Article
  6. Article
  7. Article
  8. Article
  9. The autoimmune side of heart and lung diseases.Clinical reviews in allergy & immunology · 2013
    Review
  10. [Pulmonary allergic reactions].Der Internist · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Wojciech SzczeklikDepartment of Medicine, Jagiellonian University Medical College, Skawińska 8, 31 - 066, Kraków, Poland. wszczeklik@gmail.com
Bogdan Jakieła
Dariusz Adamek
Jacek Musiał
Jagiellonian University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Churg-Strauss syndrome (CSS) is a rare systemic small-vessel vasculitis that develops in the background of bronchial asthma, which is characterized by eosinophilia and eosinophilic infiltration of various tissues. It belongs to the group of antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitides. The triggering factors and pathogenesis of CSS are still unknown. The possible role of eotaxin-3 and CCR4-related chemokines in selective recruitment of eosinophils to the target tissues in CSS has been recently suggested, but the role of eosinophilic inflammation in the development of vasculitic lesions is not completely understood. From the clinical view, two distinct phenotypes of the disease are slowly emerging depending on the ANCA-positivity status. Glucocorticoids are still the mainstay of treatment; however, data are accumulating regarding the beneficial role of novel immunosuppressants and biologic compounds, especially in patients with poorer prognosis.

Indexed as

Cardiovascular DiseasesChurg-Strauss SyndromeHumansNervous System DiseasesPhenotypePrognosisRespiratory Tract DiseasesTreatment Outcome

Identifiers

PMID21380944
OpenAlexW1969529153

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.