Evidence map›Paper›PMID 21380600›Full record

ArticleEuropean biophysics journal : EBJ2011

Imaging interactions of cationic antimicrobial peptides with model lipid monolayers using X-ray spectromicroscopy.

Bonnie O Leung, Adam P Hitchcock, Amy Won, Anatoli Ianoul, Andreas Scholl

Abstract read
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In one paragraph

Article in European biophysics journal : EBJ, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bonnie O LeungDepartment of Chemistry and Chemical Biology, McMaster University, Hamilton, ON, L8S 4M1, Canada.
Adam P Hitchcock
Amy Won
Anatoli Ianoul
Andreas Scholl

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The interaction of antimicrobial peptide anoplin with 1,2-dipalmitoyl-sn-glycero-3-[phospho-rac-(1-glycerol)] lipid monolayers was imaged with atomic force microscopy, scanning transmission X-ray microscopy, and X-ray photoemission electron microscopy. X-ray absorption spectromicroscopy of the surface revealed the domains of the phase-segregated surface to be composed of 98(±5)% lipid while the matrix consisted of a ~50:50 lipid-peptide mixture. We show X-ray spectromicroscopy to be a valuable quantitative tool for label-free imaging of lipid monolayers with antimicrobial peptides at a lateral spatial resolution below 80 nm.

Indexed as

Models, BiologicalAnti-Infective AgentsAntimicrobial Cationic PeptidesLipid BilayersMicroscopy, Atomic ForcePhosphatidylglycerolsX-Ray Absorption Spectroscopy1,2-dipalmitoylphosphatidylglycerolAnti-Infective AgentsAntimicrobial Cationic PeptidesLipid BilayersPhosphatidylglycerols

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.