ArticleNature structural & molecular biology2011
An effect of DNA sequence on nucleosome occupancy and removal.
Article in Nature structural & molecular biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 46 citations in OpenAlex.
- Initiation of base excision repair is modulated by nucleosome occupancy modifying sequences.DNA repair · 2025Article
- Natural promoters and promoter engineering strategies for metabolic regulation in Saccharomyces cerevisiae.Journal of industrial microbiology & biotechnology · 2023Review
- Obstacles and opportunities for base excision repair in chromatin.DNA repair · 2022Review
- Sophisticated Conversations between Chromatin and Chromatin Remodelers, and Dissonances in Cancer.International journal of molecular sciences · 2021Review
- Article
- Promoter Architecture and Promoter Engineering inMetabolites · 2020Review
- H2A.Z controls the stability and mobility of nucleosomes to regulate expression of the LH genes.Nature communications · 2016Article
- DNA signals at isoform promoters.Scientific reports · 2016Article
- Theoretical estimates of exposure timescales of protein binding sites on DNA regulated by nucleosome kinetics.Nucleic acids research · 2016Article
- Nucleosome architecture throughout the cell cycle.Scientific reports · 2016Article
- Suppression of pervasive noncoding transcription in embryonic stem cells by esBAF.Genes & development · 2015Article
- Fuzziness and noise in nucleosomal architecture.Nucleic acids research · 2014Article
- The chemistry of regulation of genes and other things.The Journal of biological chemistry · 2014Review
- Nucleosomes are stably evicted from enhancers but not promoters upon induction of certain pro-inflammatory genes in mouse macrophages.PloS one · 2014Article
- Nucleosome positioning and kinetics near transcription-start-site barriers are controlled by interplay between active remodeling and DNA sequence.Nucleic acids research · 2014Article
- Article
- Impact of methylation on the physical properties of DNA.Biophysical journal · 2012Article
- Nucleosome positioning: bringing order to the eukaryotic genome.Trends in cell biology · 2012Review
- Histone occupancy in vivo at the 601 nucleosome binding element is determined by transcriptional history.Molecular and cellular biology · 2011Article
- Principles of a switch.Nature chemical biology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
A barrier phases nucleosomes at the yeast (Saccharomyces cerevisiae) GAL1-GAL10 genes. Here we separate nucleosome positioning from occupancy and show that the degree of occupancy of these phased sites is predictably determined by the underlying DNA sequences. As this occupancy is increased (by sequence alteration), nucleosome removal upon induction is decreased, as is mRNA production. These results explain why promoter sequences have evolved to form nucleosomes relatively inefficiently.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.