ArticleNature chemistry2009
The rational design of nitric oxide selectivity in single-walled carbon nanotube near-infrared fluorescence sensors for biological detection.
Article in Nature chemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
64 citing papers in PubMed.
- Fluorescent Nanosensor for Indole-3-Propionic Acid Detection in Gut Health Monitoring.Advanced healthcare materials · 2026Article
- Submicrowatt-driven near-infrared luminescence from perovskite-fluoride quantum-cutting heterostructures for gas sensing.Nature communications · 2026Article
- Hetero-Functionalization of Carbon Nanotubes Termini with Single-Molecule Control.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Near-Infrared Fluorescent Single-Walled Carbon Nanotubes for Biosensing.Small (Weinheim an der Bergstrasse, Germany) · 2025Review
- ZnFeMicromachines · 2025Article
- Programming-Assisted Imaging of Cellular Nitric Oxide Efflux Gradients and Directionality via Carbon Nanotube Sensors.Small science · 2025Article
- Article
- Optical Aptamer-Based Cytokine Nanosensor Detects Macrophage Activation by Bacterial Toxins.ACS sensors · 2024Article
- Development and Evaluation of an Expedited System for Creation of Single Walled Carbon Nanotube Platforms.Carbon letters · 2024Article
- An optical aptamer-based cytokine nanosensor detects macrophage activation by bacterial toxins.bioRxiv : the preprint server for biology · 2024Article
- Carbon Nanomaterial Fluorescent Probes and Their Biological Applications.Chemical reviews · 2024Review
- Micro-engineering and nano-engineering approaches to investigate tumour ecosystems.Nature reviews. Cancer · 2023Review
- Localized Charge on Surfactant-Wrapped Single-Walled Carbon Nanotubes.The journal of physical chemistry letters · 2022Article
- Gas Sensors Based on Single-Wall Carbon Nanotubes.Molecules (Basel, Switzerland) · 2022Review
- Biosensing with Fluorescent Carbon Nanotubes.Angewandte Chemie (International ed. in English) · 2022Review
- Single-Walled Carbon Nanotube Probes for the Characterization of Biofilm-Degrading Enzymes Demonstrated againstAnalytical chemistry · 2022Article
- Detection and Imaging of the Plant Pathogen Response by Near-Infrared Fluorescent Polyphenol Sensors.Angewandte Chemie (International ed. in English) · 2022Article
- Fluorescent Biosensors Based on Silicon Nanowires.Nanomaterials (Basel, Switzerland) · 2021Review
- Emerging two-dimensional material nanozymes for theranostic nanomedicine.Biophysics reports · 2021Article
- Cellular lensing and near infrared fluorescent nanosensor arrays to enable chemical efflux cytometry.Nature communications · 2021Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A major challenge in the synthesis of nanotube or nanowire sensors is to impart selective analyte binding through means other than covalent linkages, which compromise electronic and optical properties. We synthesized a 3,4-diaminophenyl-functionalized dextran (DAP-dex) wrapping for single-walled carbon nanotubes (SWNTs) that imparts rapid and selective fluorescence detection of nitric oxide (NO), a messenger for biological signalling. The near-infrared (nIR) fluorescence of SWNT(DAP-dex) is immediately and directly bleached by NO, but not by other reactive nitrogen and oxygen species. This bleaching is reversible and shown to be caused by electron transfer from the top of the valence band of the SWNT to the lowest unoccupied molecular orbital of NO. The resulting optical sensor is capable of real-time and spatially resolved detection of NO produced by stimulating NO synthase in macrophage cells. We also demonstrate the potential of the optical sensor for in vivo detection of NO in a mouse model.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.