ArticleNature chemistry2009
Polymer nanofibre junctions of attolitre volume serve as zeptomole-scale chemical reactors.
Article in Nature chemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed.
- Microfluidic-Architected Nanoarrays/Porous Core-Shell Fibers toward Robust Micro-Energy-Storage.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Article
- Fiber-Spinning-Chemistry Method toward In Situ Generation of Highly Stable Halide Perovskite Nanocrystals.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2019Article
- Automated and Accelerated Synthesis of Indole Derivatives on a Nano-Scale.Green chemistry : an international journal and green chemistry resource : GC · 2019Article
- Microfluidic-spinning construction of black-phosphorus-hybrid microfibres for non-woven fabrics toward a high energy density flexible supercapacitor.Nature communications · 2018Article
- Stacked electrospun polymer nanofiber heterostructures with tailored stimulated emission.RSC advances · 2018Article
- Chemistry in nanoconfined water.Chemical science · 2017Article
- Enhancing the Mechanical Properties of Electrospun Nanofiber Mats through Controllable Welding at the Cross Points.Macromolecular rapid communications · 2017Article
- Multifunctional Polymer Nanofibers: UV Emission, Optical Gain, Anisotropic Wetting, and High Hydrophobicity for Next Flexible Excitation Sources.ACS applied materials & interfaces · 2015Article
- Nanowire liquid pumps.Nature nanotechnology · 2013Article
- Discreteness-induced concentration inversion in mesoscopic chemical systems.Nature communications · 2012Article
- Energy transfer dyads based on Nile Red.Tetrahedron letters · 2009Article
- Miniaturization: Chemistry at the crossroads.Nature chemistry · 2009Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Methods allowing chemical reactions to be carried out on ultra-small scales in a controllable fashion are potentially important for a number of disciplines, including molecular electronics, photonics and molecular biology, and may provide fundamental insight into chemistry in confined spaces. Ultra-small-scale reactions also circumvent potential problems associated with reagent and product toxicity, and reduce energy consumption and waste generation. Here, we report a technique for performing chemical reactions on a zeptomole (10(-21) mol) scale. We show that electrospun polymer nanofibres with a diameter of 100-300 nm can be loaded with reactants, and that the junctions formed between crossed nanofibres can function as attolitre-volume reactors. Exposure to heat or solvent vapours fuses the fibres and initiates the reaction. The reaction products can be analysed directly within the nanofibre junctions by fluorescence measurements and mass spectrometry, and solvent extraction of multiple reactors allows product identification by common micromethods such as high-performance liquid chromatography-mass spectrometry.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.