ArticleThe American journal of gastroenterology2011
Understanding gastrointestinal distress: a framework for clinical practice.
Article in The American journal of gastroenterology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Development of an online library of patient-reported outcome measures in gastroenterology: the GI-PRO database.The American journal of gastroenterology · 2014Pooled it
- The Relationship Between Trauma Exposure, PTSD Symptoms, and Gastrointestinal Symptoms.International journal of behavioral medicine · 2026Article
- Impact of Mānuka Honey on Symptoms and Quality of Life in Individuals With Functional Dyspepsia: Protocol for a Feasibility Randomized Controlled Trial.JMIR research protocols · 2025Article
- Gastrointestinal symptoms and nutritional intake among participants in a non-professional cycling event.European journal of applied physiology · 2025Article
- Gut Microbial Composition Is Associated with Symptom Self-Report in Trauma-Exposed Iraq and Afghanistan Veterans.Neurotrauma reports · 2025Article
- Tracking changes in autonomic function by coupled analysis of wavelet-based dispersion of heart rate variability and gastrointestinal symptom severity in individuals with hypermobile Ehlers-Danlos syndrome.Frontiers in neurology · 2024Article
- Article
- The association between comorbidities and stigma among breast cancer survivors.Scientific reports · 2022Article
- Prevalence and Characteristics of Abdominal Pain in the United States.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2021Article
- Chronic Constipation in the United States: Results From a Population-Based Survey Assessing Healthcare Seeking and Use of Pharmacotherapy.The American journal of gastroenterology · 2020Article
- Analysis of Answers to Queries among Anonymous Users with Gastroenterological Problems on an Internet Forum.International journal of environmental research and public health · 2020Article
- The Role of Chronic Stress in Normal Visceroception: Insights From an Experimental Visceral Pain Study in Healthy Volunteers.Frontiers in psychiatry · 2020Article
- Population-based assessment of gastrointestinal symptoms and diseases: Cappadocia Cohort, Turkey.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2019Article
- Burden of Gastrointestinal Symptoms in the United States: Results of a Nationally Representative Survey of Over 71,000 Americans.The American journal of gastroenterology · 2018Article
- The stress concept in gastroenterology: from Selye to today.F1000Research · 2017Review
- Development of the NIH Patient-Reported Outcomes Measurement Information System (PROMIS) gastrointestinal symptom scales.The American journal of gastroenterology · 2014Article
- Construct validity of the Patient-Reported Outcomes Measurement Information System gastrointestinal symptom scales in systemic sclerosis.Arthritis care & research · 2014Article
- GERD symptoms in the general population: prevalence and severity versus care-seeking patients.Digestive diseases and sciences · 2014Article
- Comparing PROMIS computer-adaptive tests to the Brief Symptom Inventory in patients with prostate cancer.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2014Article
- Struggling with food and eating--life after major upper gastrointestinal surgery.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
We describe a framework to help clinicians think about health-related quality of life in their gastrointestinal (GI) patients. We introduce "GI distress" as a clinically relevant concept and explain how it may result from physical symptoms, cognitions, and emotions. The GI distress framework suggests that providers should divide GI physical symptoms into four categories: pain, gas/bloat, altered defecation, and foregut symptoms. We describe how these physical symptoms can be amplified by maladaptive cognitions, including external locus of control, catastrophizing, and anticipation anxiety. We suggest determining the level of embarrassment from GI symptoms and asking about stigmatization. GI patients may also harbor emotional distress from their illness and may exhibit visceral anxiety marked by hypervigilance, fear, and avoidance of GI sensations. Look for signs of devitalization, indicated by inappropriate fatigue. When appropriate, screen for suicidal ideations. Finally, we provide a list of high-yield questions to screen for these maladaptive cognitions and emotions, and explain how the GI distress framework can be used in clinical practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.