Evidence map›Paper›PMID 21377267›Full record

ReviewCancer letters2011

Update on KSHV epidemiology, Kaposi Sarcoma pathogenesis, and treatment of Kaposi Sarcoma.

Thomas S Uldrick, Denise Whitby

Registry-linked trialAbstract readReview
In one paragraph

Review in Cancer letters, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01495598 (A Phase I/II Study of the Safety, Pharmacokinetics and Efficacy of Pomalidomide), which is not on this map. Cited by 85 papers.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01495598 phase1 / phase2completednot on this mapstarted 2012, after this paper: background citation

A Phase I/II Study of the Safety, Pharmacokinetics and Efficacy of Pomalidomide (CC-4047) in the Treatment of Kaposi Sarcoma in Individuals With or Without HIV

TypeinterventionalSponsorNational Cancer Institute (NCI)Ran2012 to 2022Enrolled28ConditionsKaposi Sarcoma, Sarcoma, KaposiArmsPomalidomide
3 · Its place in the literature

Who cites it

85 citing papers in PubMed.

  1. Phase II study of bevacizumab in patients with HIV-associated Kaposi's sarcoma receiving antiretroviral therapy.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2012
    Trial
  2. Review
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25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Thomas S UldrickHIV and AIDS Malignancy Branch, National Cancer Institute/NIH, Bethesda, MD 20892, USA. uldrickts@mail.nih.gov
Denise Whitby

Funding

Intramural NIH HHS Z99 CA999999NCI NIH HHS N01 CO012400NCI NIH HHS N01-CO-12400
6 · The paper itself

Abstract

Much has been learned since the discovery of KSHV in 1994 about its epidemiology and pathology but much of what has been learned has yet to be translated into clinical practice. In this review, we survey the current state of knowledge on KSHV epidemiology and KS pathogenesis and highlight therapeutic opportunities in both the developed and developing world.

Indexed as

AnimalsAnti-Retroviral AgentsHerpesvirus 8, HumanHIV InfectionsHumansImmune SystemInflammationMicePrevalenceRisk FactorsSarcoma, KaposiVascular Endothelial Growth Factor AVirus ReplicationAnti-Retroviral AgentsVascular Endothelial Growth Factor A

Identifiers

PMID21377267
PMCPMC3085592

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.