Evidence map›Paper›PMID 21376666›Full record

ReviewTrends in molecular medicine2011

Skin microbiome: genomics-based insights into the diversity and role of skin microbes.

Heidi H Kong

Registry-linked trialAbstract readReview
In one paragraph

Review in Trends in molecular medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05139628 (The Impact of Skin Colonization at the Peripheral Venous Catheter Insertion Sites on Catheter Tip Colonization and Catheter Related Blood Stream Infections Among Pediatric Oncology Patients.), which is not on this map. Cited by 113 papers.

0numbers the graph read from it
0cells of the map it votes in
113citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05139628 unknown statusnot on this mapstarted 2023, after this paper: background citation

The Impact of Skin Colonization at the Peripheral Venous Catheter Insertion Sites on Catheter Tip Colonization and Catheter Related Blood Stream Infections Among Pediatric Oncology Patients.

TypeobservationalSponsorAssiut UniversityRan2023 to 2024Enrolled100ConditionsCatheter-Related InfectionsArmsmicrobiological identification of samples (skin and blood samples)
3 · Its place in the literature

Who cites it

113 citing papers in PubMed.

  1. Insights into bacterial colonization of intensive care patients' skin: the effect of chlorhexidine daily bathing.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2015
    Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Gut Microbiome and Estrogen.Journal of menopausal medicine · 2025
    Review
  10. Cutaneous and Gut Dysbiosis in Alopecia Areata: A Review.JID innovations : skin science from molecules to population health · 2025
    Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Microenvironmental host-microbe interactions in chronic inflammatory skin diseases.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2024
    Review
  16. Effective use of skin microbiome signatures for fingerprint identification.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  17. Article
  18. Article
  19. Review
  20. Article

53 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Heidi H KongDermatology Branch, Center for Cancer Research, National Cancer Institute, NIH, 10 Center Drive, Bldg 10, Rm 12N238, Bethesda, MD 20892, USA. konghe@mail.nih.gov

Funding

Studies of Skin Microflora in Healthy Individuals and Atopic Dermatitis PatientsZIABC010938 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI KONG, HEIDI · 2009 to 2021
$5.4M
Intramural NIH HHS ZIA BC010938NIAMS NIH HHS AR057504NIAMS NIH HHS UH2 AR057504
6 · The paper itself

Abstract

Recent advances in DNA sequencing methodology have facilitated studies of human skin microbes that circumvent difficulties in isolating and characterizing fastidious microbes. Sequence-based approaches have identified a greater diversity of cutaneous bacteria than studies using traditional cultivation techniques. However, improved sequencing technologies and analytical methods are needed to study all skin microbes, including bacteria, archaea, fungi, viruses and mites, and how they interact with each other and their human hosts. This review discusses current skin microbiome research, with a primary focus on bacteria, and the challenges facing investigators striving to understand how skin microorganisms contribute to health and disease.

Indexed as

BacteriaAnimalsArchaeaBiodiversityDNA, BacterialFungiGenomicsHumansMetagenomeMitesRNA, Ribosomal, 16SSequence Analysis, DNASkinVirusesDNA, BacterialRNA, Ribosomal, 16S

Identifiers

PMID21376666
PMCPMC3115422

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.