ArticleJournal of translational medicine2011
Hypoxia-induced down-regulation of microRNA-449a/b impairs control over targeted SERPINE1 (PAI-1) mRNA - a mechanism involved in SERPINE1 (PAI-1) overexpression.
Article in Journal of translational medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Loss of TARBP2 Drives the Progression of Hepatocellular CarcinomaFrontiers in oncology · 2021Article
- MicroRNA‑449a regulates the progression of brain aging by targeting SCN2B in SAMP8 mice.International journal of molecular medicine · 2020Article
- Non-coding RNAs in lung cancer.Oncoscience · 2014Review
- Hypoxia: a master regulator of microRNA biogenesis and activity.Free radical biology & medicine · 2013Review
- MicroRNAs and the cancer phenotype: profiling, signatures and clinical implications.Genome medicine · 2013Review
- MicroRNAs and lung cancers: from pathogenesis to clinical implications.Frontiers of medicine · 2012Review
- The miR-143/-145 cluster regulates plasminogen activator inhibitor-1 in bladder cancer.British journal of cancer · 2012Article
- Hypoxia-induced down-regulation of microRNA-34a promotes EMT by targeting the Notch signaling pathway in tubular epithelial cells.PloS one · 2012Article
Corrections and comments
- Erratum for
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
After publication of our article 1, we realized the need for posting a correction note in order to prevent i) overinterpretation of some results by the readers and ii) concerns about potentially unintended misguidance by the authors.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.