ArticleMicrobial biotechnology2011
Comparative genomics of Lactobacillus.
Article in Microbial biotechnology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
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Who cites it
67 citing papers in PubMed, 132 citations in OpenAlex.
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- Screening and Comparative Genomics of Probiotic Lactic Acid Bacteria from Bee Bread ofMicroorganisms · 2025Article
- Bacillus subtilis SOM8 isolated from sesame oil meal for potential probiotic application in inhibiting human enteropathogens.BMC microbiology · 2024Article
- Genomic Analysis and In Vitro Investigation of the Hop Resistance Phenotype of Two NovelMicroorganisms · 2023Article
- Do advanced glycation end products contribute to food allergy?Frontiers in allergy · 2023Review
- Bacterial diversity of stingless bee honey in Yunnan, China: isolation and genome sequencing of a novel acid-resistantFrontiers in bioengineering and biotechnology · 2023Article
- Application of 16S rRNA virtual RFLP for the discrimination of some closely taxonomic-related lactobacilli species.Journal, genetic engineering & biotechnology · 2022Article
- Comparative genomics of Lactobacillaceae from the gut of honey bees, Apis mellifera, from the Eastern United States.G3 (Bethesda, Md.) · 2022Article
- Genomic diversity of genusMicrobial genomics · 2022Article
- Lactobacilli and human dental caries: more than mechanical retention.Microbiology (Reading, England) · 2022Article
- Isolation, identification and characterization ofHeliyon · 2021Article
- Comparative Genomics of 42Antibiotics (Basel, Switzerland) · 2021Article
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- The Complete Genome of ProbioticGenes · 2020Article
- Molecular typing tools for identifying and characterizing lactic acid bacteria: a review.Food science and biotechnology · 2020Review
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- The local transcriptional regulators SacR1 and SacR2 act as repressors of fructooligosaccharides metabolism in Lactobacillus plantarum.Microbial cell factories · 2020Article
- Comparative Genomics Analysis ofGenes · 2020Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The genus Lactobacillus includes a diverse group of bacteria consisting of many species that are associated with fermentations of plants, meat or milk. In addition, various lactobacilli are natural inhabitants of the intestinal tract of humans and other animals. Finally, several Lactobacillus strains are marketed as probiotics as their consumption can confer a health benefit to host. Presently, 154 Lactobacillus species are known and a growing fraction of these are subject to draft genome sequencing. However, complete genome sequences are needed to provide a platform for detailed genomic comparisons. Therefore, we selected a total of 20 genomes of various Lactobacillus strains for which complete genomic sequences have been reported. These genomes had sizes varying from 1.8 to 3.3 Mb and other characteristic features, such as G+C content that ranged from 33% to 51%. The Lactobacillus pan genome was found to consist of approximately 14 000 protein-encoding genes while all 20 genomes shared a total of 383 sets of orthologous genes that defined the Lactobacillus core genome (LCG). Based on advanced phylogeny of the proteins encoded by this LCG, we grouped the 20 strains into three main groups and defined core group genes present in all genomes of a single group, signature group genes shared in all genomes of one group but absent in all other Lactobacillus genomes, and Group-specific ORFans present in core group genes of one group and absent in all other complete genomes. The latter are of specific value in defining the different groups of genomes. The study provides a platform for present individual comparisons as well as future analysis of new Lactobacillus genomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.