Evidence map›Paper›PMID 2137554›Full record

ArticleMolecular and cellular biology1990

Nuclear transport of proteins translated in vitro from SP6 plasmid-generated mRNAs.

V K Parnaik, P K Kennady

Abstract read
In one paragraph

Article in Molecular and cellular biology, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

V K ParnaikCentre for Cellular and Molecular Biology, Hyderabad, India.
P K Kennady

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A sensitive and versatile assay is described for the nuclear transport of 35S-labeled proteins obtained by the in vitro translation of SP6 plasmid-generated mRNAs. A specific nuclear accumulation of greater than 20-fold is observed for the transformation-related nuclear proteins, p53 and E1b, and the nuclear enzyme, thymidine kinase, whereas transport of the nonnuclear proteins, dihydrofolate reductase and simian virus 40 small t antigen, is negligible within 30 min.

Indexed as

Adenosine TriphosphateAdenovirus Early ProteinsBiological TransportCell-Free SystemCell NucleusCytoplasmDNA, RecombinantFluorescent Antibody TechniqueIn Vitro TechniquesNuclear ProteinsOncogene ProteinsOncogene Proteins, ViralPhosphoproteinsPlasmidsProtein BiosynthesisThymidine KinaseAdenosine TriphosphateAdenovirus Early ProteinsDNA, RecombinantNuclear ProteinsOncogene ProteinsOncogene Proteins, ViralPhosphoproteinsThymidine KinaseTumor Suppressor Protein p53

Identifiers

PMID2137554
PMCPMC361022

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.