Evidence map›Paper›PMID 21375430›Full record

ArticleAIDS patient care and STDs2011

Buffering effects of general and medication-specific social support on the association between substance use and HIV medication adherence.

Keren Lehavot, David Huh, Karina L Walters, Kevin M King, Michele P Andrasik, Jane M Simoni

Abstract read
In one paragraph

Article in AIDS patient care and STDs, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

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  6. Adult Cancer Patient Recruitment and Enrollment into Cell Phone Text Message Trials.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2016
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  10. Health status, sexual and drug risk, and psychosocial factors relevant to postrelease planning for HIV+ prisoners.Journal of correctional health care : the official journal of the National Commission on Correctional Health Care · 2013
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Keren LehavotDepartment of Psychology, University of Washington, Seattle, 98195, USA. klehavot@u.washington.edu
David Huh
Karina L Walters
Kevin M King
Michele P Andrasik
Jane M Simoni
University of Washington · US

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Judith Tsui · 1988 to 2026
$104.9M
Methods and Data CoreR24HD042828 · NICHD · UNIVERSITY OF WASHINGTON · PI CURRAN, SARA R. · 2002 to 2016
$9.3M
The ITZA Program: Indigenous HIV/AIDS Research Training 3 (IHART3) ProgramR25MH084565 · NIMH · UNIVERSITY OF WASHINGTON · PI Teresa A Evans-Campbell, Michelle D Johnson-Jennings · 2009 to 2026
$3.7M
PEER SUPPORT TO ENHANCE ANTIRETROVIRAL ADHERENCER01MH058986 · NIMH · YESHIVA UNIVERSITY · PI SIMONI, JANE MARIE · 1999 to 2006
$2.8M
Mentoring Diverse Scientists in HIV Research on Substance Abuse and Mental HealthK24DA031613 · NIDA · UNIVERSITY OF WASHINGTON · PI WALTERS, KARINA LYNN · 2011 to 2015
$948k
NIAID NIH HHS P30 AI027757NICHD NIH HHS R24 HD042828NIDA NIH HHS K24 DA031613NIMH NIH HHS R01 MH58986NIMH NIH HHS R25 MH084565
6 · The paper itself

Abstract

The success of highly active antiretroviral therapy (HAART) among persons living with HIV is largely dependent on strict medication adherence. Recent research suggests that alcohol and other drug use (AOD) may be an important barrier to HAART adherence. In this study, we examined the impact of AOD on HAART adherence as well as the moderating effects of general and medication-specific social support. The data were collected as part of a longitudinal randomized control trial with 224 HIV-positive patients at an HIV primary care clinic in the northwestern United States. Findings indicated that AOD use was negatively associated with HAART adherence and that medication-specific (but not general) social support moderated the AOD-adherence association at 3 (but not at 6 or 9) months. Results indicate the importance of medication-specific social support to treat comorbid AOD use and HIV; implications for future research and intervention programs for HIV-positive AOD users are discussed.

Indexed as

Patient ComplianceSocial SupportAdultAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveFemaleHIV InfectionsHumansMaleMiddle AgedSocioeconomic FactorsSubstance-Related DisordersYoung AdultAnti-HIV Agents

Identifiers

PMID21375430
PMCPMC3048831
OpenAlexW112621234

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.