Evidence map›Paper›PMID 21374771›Full record

ArticleAngewandte Chemie (International ed. in English)2011

Leiodermatolide, a potent antimitotic macrolide from the marine sponge Leiodermatium sp.

Ian Paterson, Stephen M Dalby, Jill C Roberts, Guy J Naylor, Esther A Guzmán, Richard Isbrucker, Tara P Pitts, Pat Linley, Daniela Divlianska, John K Reed and 1 more

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
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  17. Structure reassignment of laurefurenynes A and B by computation and total synthesis.Chemistry (Weinheim an der Bergstrasse, Germany) · 2013
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ian PatersonUniversity Chemical Laboratory, Lensfield Road, Cambridge, CB2 1EW UK. ip100@cam.ac.uk
Stephen M Dalby
Jill C Roberts
Guy J Naylor
Esther A Guzmán
Richard Isbrucker
Tara P Pitts
Pat Linley
Daniela Divlianska
John K Reed
Amy E Wright

Funding

Discovery of Novel Antitumor Agents Effective Against Pancreatic CancerR01CA093455 · NCI · HARBOR BRANCH OCEANOGRAPHIC INST, INC. · PI WRIGHT, AMY ELIZABETH · 2003 to 2012
$2.0M
Discovery of Novel Antitumor Agents Effective Against Pancreatic CancerR56CA093455 · NCI · FLORIDA ATLANTIC UNIVERSITY · PI WRIGHT, AMY ELIZABETH · 2008 to 2009
$489k
NCI NIH HHS CA-93455NCI NIH HHS R01 CA093455NCI NIH HHS R56 CA093455
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntimitotic AgentsCell Line, TumorCell ProliferationMacrolidesMitosisMolecular StructureNuclear Magnetic Resonance, BiomolecularOceans and SeasPoriferaAntimitotic AgentsleiodermatolideMacrolides

Identifiers

PMID21374771
PMCPMC3875319

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.