ArticleDer Unfallchirurg2011
[Necrotizing fasciitis. 2011 update].
Article in Der Unfallchirurg, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 39 citations in OpenAlex.
- Necrotising Soft Tissue Infections: A Single Center's Case Series.International wound journal · 2026Article
- Necrotizing soft tissue infection of the shoulder caused by non-penetrating trauma - a case report.Journal of cardiothoracic surgery · 2025Article
- [Necrotizing fasciitis].Chirurgie (Heidelberg, Germany) · 2024Review
- Giant Ulcer with Necrosis on Right Vulva, Groin, and Thigh-- A Case of Necrotizing Fasciitis Associated with Erythematous Pemphigus.Clinical, cosmetic and investigational dermatology · 2024Article
- Severe necrotizing soft tissue infections-Is wound microbiology a prognostic factor for clinical outcome?International wound journal · 2023Article
- The LRINEC Score-An Indicator for the Course and Prognosis of Necrotizing Fasciitis?Journal of clinical medicine · 2022Article
- [32/f-chills and fever : Preparation for the medical specialist examination-Part 10].Der Unfallchirurg · 2021Article
- Novel Clinical Risk Scoring Model for Predicting Amputation in Patients With Necrotizing Fasciitis: The ANF Risk Scoring System.Frontiers in medicine · 2021Article
- [Treatment of a necrotizing soft tissue infection].Der Unfallchirurg · 2020Article
- Multidisciplinary treatment of a patient with necrotizing fasciitis caused byWorld journal of clinical cases · 2019Article
- Necrotizing fasciitis and the midterm outcomes after survival.SAGE open medicine · 2019Article
- Necrotizing fasciitis: treatment concepts and clinical results.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2018Article
- [Necrotizing fasciitis of the hand and forearm : Acute surgical treatment and defect reconstruction with MatriDerm® and split-thickness skin graft].Der Unfallchirurg · 2018Article
- Severe Fournier's gangrene-a conjoint challenge of gynaecology and plastic surgery.Journal of surgical case reports · 2017Article
- [Necrotizing fasciitis - a clinical diagnosis].Der Orthopade · 2016Review
- [Eyelid swelling with reduced general state of health].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2016Article
- [Pyoderma gangrenosum after intramedullary nailing of tibial shaft fracture: A differential diagnosis to necrotizing fasciitis].Der Unfallchirurg · 2015Article
- [Benign subcutaneous emphysema after nail penetration. Case report and important differential diagnoses].Der Unfallchirurg · 2014Article
- Necrotizing fasciitis in a young patient with acute myeloid leukemia - a diagnostic challenge.Patient safety in surgery · 2014Article
- [Hyperbaric oxygen therapy for necrotizing soft tissue infections: contra].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2012Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Necrotizing fasciitis belongs to a group of complicated soft tissue infections that can be even life threatening. Despite growing knowledge about its etiology, predictors, and the clinical progression, the mortality remains at a high level with 20%. A relevant reduction can be achieved only by an early diagnosis followed by consistent therapy. The clinical findings in about 75% of the cases are pain out of proportion, edema and tenderness, blisters, and erythema. It is elementary to differentiate a necrotizing or a non-necrotizing soft tissue infection early. In uncertain cases it can be necessary to perform a surgical exploration to confirm the diagnosis. The histopathologic characteristics are the fascial necrosis, vasculitis, thrombosis of perforating veins, the presence of the disease-causing bacteria as well as inflammatory cells like macrophages and polymorphonuclear granulocytes. Secondly, both the cutis and the muscle can be affected. In many cases there is a disproportion of the degree of local and systemic symptoms. Depending on the infectious agents there are two main types: type I is a polymicrobial infection and type II is a more invasive, serious, and fulminant monomicrobial infection mostly caused by group A Streptococcus pyogenes.Invasive, severe forms of streptococcal infections seem to occur more often in recent years. Multimodal and interdisciplinary therapy should be based on radical surgical débridement, systemic antibiotic therapy as well as enhanced intensive care therapy, which is sometimes combined with immunoglobulins (in streptococcal or staphylococcal infections) or hyperbaric oxygen therapy (HBOT, in clostridial infections). For wound care of extensive soft tissue defects vacuum-assisted closure has shown its benefit.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.