Evidence map›Paper›PMID 21373791›Full record

SynthesisPsychopharmacology2011

Delayed reward discounting and addictive behavior: a meta-analysis.

James MacKillop, Michael T Amlung, Lauren R Few, Lara A Ray, Lawrence H Sweet, Marcus R Munafò

4 registry-linked trialsAbstract readMeta-Analysis
In one paragraph

Synthesis in Psychopharmacology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 557 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
557citing papers in PubMed, 13 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03335735 nacompletednot on this mapstarted 2017, after this paper: background citation

Pilot Trial Leveraging Smartphone-paired Breathalyzers and Loss- and Gain-framed Text Notifications for Reducing Drinking Driving

TypeinterventionalSponsorUniversity of PennsylvaniaRan2017 to 2018Enrolled58ConditionsAlcohol Drinking, Alcohol Intoxication, Alcohol Impairment, DriveArmsLoss-framed text message, Gain-Framed text message
NCT04086576 nacompletednot on this mapstarted 2016, after this paper: background citation

Reducing Risky Drinking Using Smartphone Paired Breathalyzer

TypeinterventionalSponsorUniversity of PennsylvaniaRan2016 to 2017Enrolled20ConditionsAlcohol Drinking, Alcohol IntoxicationArmsAlcohoot, BACtrack Mobile Pro, DRIVESAFE Evoc, BACtrack Vio, Drinkmate
NCT05229120 nacompletednot on this mapstarted 2022, after this paper: background citation

Improving Delay Discounting to Decrease Harsh Parenting Among Parents Receiving Substance Use Treatment in Low Income Community

TypeinterventionalSponsorHenry Ford Health SystemRan2022 to 2023Enrolled38ConditionsBehavioral HealthArmsEpisodic Future Thinking
NCT05879198 nacompletednot on this mapstarted 2023, after this paper: background citation

Train Your Brain: A Pilot Project to Improve Memory and Decision Making to Improve Outcomes Among Youth

TypeinterventionalSponsorHenry Ford Health SystemRan2023 to 2023Enrolled23ConditionsBehavior, HealthArmsComputer-based Intervention
3 · Its place in the literature

Who cites it

557 citing papers in PubMed, 13 syntheses or guidelines pooled it.

  1. Reward Processing in Binge Eating and Harmful Drinking: A Systematic Review.The International journal of eating disorders · 2026
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  13. A systematic review and meta-analysis of delay discounting and cannabis use.Experimental and clinical psychopharmacology · 2021
    Pooled it
  14. Differential Responses to Cigarette Package Labeling Alternatives Among Adults Who Smoke: Results From a Randomized Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Trial
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  18. Working Memory Training Reduces Cigarette Smoking Among Low-Income Individuals With Elevated Delay Discounting.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022
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  20. Article

497 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

James MacKillopDepartment of Psychology, University of Georgia, Athens, GA 30602, USA. jmackill@uga.edu
Michael T Amlung
Lauren R Few
Lara A Ray
Lawrence H Sweet
Marcus R Munafò

Funding

Vulnerability to Drug Use & HIV: Advancing Prevention for Rural African AmericansP30DA027827 · NIDA · UNIVERSITY OF GEORGIA · PI BRODY, GENE H. · 2009 to 2018
$10.2M
Enhancing Alcoholism Pharmacotherapy Research via Behavioral EconomicsK23AA016936 · NIAAA · UNIVERSITY OF GEORGIA · PI MACKILLOP, JAMES · 2008 to 2012
$805k
British Heart FoundationDepartment of HealthMedical Research CouncilNIAAA NIH HHS AA 016936NIAAA NIH HHS K23 AA016936NIDA NIH HHS P30 DA027827
6 · The paper itself

Abstract

rationaleDelayed reward discounting (DRD) is a behavioral economic index of impulsivity and numerous studies have examined DRD in relation to addictive behavior. To synthesize the findings across the literature, the current review is a meta-analysis of studies comparing DRD between criterion groups exhibiting addictive behavior and control groups.

objectivesThe meta-analysis sought to characterize the overall patterns of findings, systematic variability by sample and study type, and possible small study (publication) bias.

methodsLiterature reviews identified 310 candidate articles from which 46 studies reporting 64 comparisons were identified (total N=56,013).

resultsFrom the total comparisons identified, a small magnitude effect was evident (d= .15; p< .00001) with very high heterogeneity of effect size. Based on systematic observed differences, large studies assessing DRD with a small number of self-report items were removed and an analysis of 57 comparisons (n=3,329) using equivalent methods and exhibiting acceptable heterogeneity revealed a medium magnitude effect (d= .58; p< .00001). Further analyses revealed significantly larger effect sizes for studies using clinical samples (d= .61) compared with studies using nonclinical samples (d=.45). Indices of small study bias among the various comparisons suggested varying levels of influence by unpublished findings, ranging from minimal to moderate.

conclusionsThese results provide strong evidence of greater DRD in individuals exhibiting addictive behavior in general and particularly in individuals who meet criteria for an addictive disorder. Implications for the assessment of DRD and research priorities are discussed.

Indexed as

Models, PsychologicalRewardAlcohol DrinkingBehavior, AddictiveDecision MakingHumansSubstance-Related Disorders

Identifiers

PMID21373791
PMCPMC3201846

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.