ArticleNature protocols2011
Dynamic clamp with StdpC software.
Article in Nature protocols, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Combinatorial logic of Nav channels in nociceptor excitability: Different degrees of synergy define distinct neuronal groups.bioRxiv : the preprint server for biology · 2026Article
- Dynamic Clamp Methods to Investigate Impaired Neuronal Excitability Associated with Autism.Journal of visualized experiments : JoVE · 2025Article
- Nav1.8: Intrinsic limits on the functional effect of abrogation in DRG neurons.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Functional mapping of the molluscan brain guided by synchrotron X-ray tomography.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Synaptic alterations in pyramidal cells following genetic manipulation of neuronal excitability in monkey prefrontal cortex.Journal of neurophysiology · 2025Article
- Interplay of Nav1.8 and Nav1.7 channels drives neuronal hyperexcitability in neuropathic pain.The Journal of general physiology · 2024Article
- IThe Journal of physiology · 2023Article
- Bursting emerges from the complementary roles of neurons in a four-cell network.Journal of neurophysiology · 2022Article
- Article
- Dynamics of a Mutual Inhibition Circuit between Pyramidal Neurons Compared to Human Perceptual Competition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- The unlimited potential of the great pond snail,eLife · 2020Article
- Automatic Adaptation of Model Neurons and Connections to Build Hybrid Circuits with Living Networks.Neuroinformatics · 2020Article
- Article
- Command or Obey? Homologous Neurons Differ in Hierarchical Position for the Generation of Homologous Behaviors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Nonlinear effects of hyperpolarizing shifts in activation of mutant NaJournal of neurophysiology · 2017Article
- Analogue modulation of back-propagating action potentials enables dendritic hybrid signalling.Nature communications · 2016Article
- The central pattern generator underlying swimming in Dendronotus iris: a simple half-center network oscillator with a twist.Journal of neurophysiology · 2016Article
- Synapse-specific expression of calcium-permeable AMPA receptors in neocortical layer 5.The Journal of physiology · 2016Article
- Human Na(v)1.8: enhanced persistent and ramp currents contribute to distinct firing properties of human DRG neurons.Journal of neurophysiology · 2015Article
- High-speed dynamic-clamp interface.Journal of neurophysiology · 2015Article
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Authors and funding
7 authors.
Funding
Abstract
Dynamic clamp is a powerful method that allows the introduction of artificial electrical components into target cells to simulate ionic conductances and synaptic inputs. This method is based on a fast cycle of measuring the membrane potential of a cell, calculating the current of a desired simulated component using an appropriate model and injecting this current into the cell. Here we present a dynamic clamp protocol using free, fully integrated, open-source software (StdpC, for spike timing-dependent plasticity clamp). Use of this protocol does not require specialist hardware, costly commercial software, experience in real-time operating systems or a strong programming background. The software enables the configuration and operation of a wide range of complex and fully automated dynamic clamp experiments through an intuitive and powerful interface with a minimal initial lead time of a few hours. After initial configuration, experimental results can be generated within minutes of establishing cell recording.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.