Evidence map›Paper›PMID 21372810›Full record

ArticleNature protocols2011

Comprehensive cluster analysis with Transitivity Clustering.

Tobias Wittkop, Dorothea Emig, Anke Truss, Mario Albrecht, Sebastian Böcker, Jan Baumbach

Abstract read
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In one paragraph

Article in Nature protocols, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
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  7. A multistage mathematical approach to automated clustering of high-dimensional noisy data.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  8. Diversity of the metal-transporting P1B-type ATPases.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2014
    Article
  9. Article
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  12. Article
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  17. The ins and outs of algal metal transport.Biochimica et biophysica acta · 2012
    Review
  18. DEFOG: discrete enrichment of functionally organized genes.Integrative biology : quantitative biosciences from nano to macro · 2012
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tobias WittkopBuck Institute for Age Research, Novato, California, USA.
Dorothea Emig
Anke Truss
Mario Albrecht
Sebastian Böcker
Jan Baumbach

Funding

Informatic Profiling of Clinically Relevant MutationR01LM009722 · NLM · UNIVERSITY OF WASHINGTON · PI MOONEY, SEAN DAVID · 2007 to 2014
$3.5M
NLM NIH HHS R01 LM009722
6 · The paper itself

Abstract

Transitivity Clustering is a method for the partitioning of biological data into groups of similar objects, such as genes, for instance. It provides integrated access to various functions addressing each step of a typical cluster analysis. To facilitate this, Transitivity Clustering is accessible online and offers three user-friendly interfaces: a powerful stand-alone version, a web interface, and a collection of Cytoscape plug-ins. In this paper, we describe three major workflows: (i) protein (super)family detection with Cytoscape, (ii) protein homology detection with incomplete gold standards and (iii) clustering of gene expression data. This protocol guides the user through the most important features of Transitivity Clustering and takes ∼1 h to complete.

Indexed as

Cluster AnalysisSoftwareComputational BiologyDatabases, Nucleic AcidDatabases, ProteinGene Expression ProfilingInternetMolecular Sequence DataPattern Recognition, AutomatedSequence AlignmentSequence AnalysisSequence HomologyUser-Computer Interface

Identifiers

PMID21372810

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.