Evidence map›Paper›PMID 21371217›Full record

ArticleTropical medicine & international health : TM & IH2011

Differing spectrum of HIV-associated ophthalmic disease among patients starting antiretroviral therapy in India and South Africa.

Sophia Pathai, Clare Gilbert, Helen A Weiss, Matthew McNally, Stephen D Lawn

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Tropical medicine & international health : TM & IH, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Cytomegalovirus retinitis and HIV: Case reviews from KwaZulu-Natal Province, South Africa.South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde · 2017
    Article
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Sophia PathaiDepartment of Clinical Research, London School of Hygiene and Tropical Medicine, UK. Sophia.Pathai@lshtm.ac.uk
Clare Gilbert
Helen A Weiss
Matthew McNally
Stephen D Lawn
London School of Hygiene & Tropical Medicine · GBDesmond Tutu HIV Foundation · ZAMedical Research Council · GB

Funding

Medical Research Council G0700837Wellcome Trust
6 · The paper itself

Abstract

Differences in the prevalence and spectrum of HIV-associated ophthalmic disease in Africa and Asia are not well documented. We studied two comparable cohorts of patients initiating antiretroviral therapy in Mumbai, India, and Cape Town, South Africa. The prevalence of HIV-associated ophthalmic disease was higher in the Indian population (17.5%) than in the South African population (12.1%). This was largely because of vitreo-retinal opportunistic infections (11.4%vs. 2.6%, respectively), notably cytomegalovirus retinitis. This difference persisted after adjusting for confounding factors (adjusted odds ratio=11.32, 95% confidence interval: 2.67-48.13), confirming a marked geographical difference in the prevalence of HIV-associated retinal disease.

Indexed as

AdolescentAdultAge DistributionAntiretroviral Therapy, Highly ActiveCD4 Lymphocyte CountCytomegalovirus RetinitisEye DiseasesFemaleHIV InfectionsHumansIndiaMaleMiddle AgedOpportunistic InfectionsPrevalenceSex Distribution

Identifiers

PMID21371217
PMCPMC3128924
OpenAlexW2150865595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.