Evidence map›Paper›PMID 21370438›Full record

ArticlePediatric blood & cancer2011

Polycythemia in an infant secondary to granulocyte transfusions.

Olufolake Adisa, Jeanne E Hendrickson, Courtney K Hopkins, Howard M Katzenstein, Cassandra D Josephson

Abstract readCase Reports
In one paragraph

Article in Pediatric blood & cancer, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Olufolake AdisaAflac Cancer Center and Blood Disorders Service, Children's Healthcare of Atlanta, Division of Pediatric Hematology/Oncology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
Jeanne E Hendrickson
Courtney K Hopkins
Howard M Katzenstein
Cassandra D Josephson
Children's Healthcare of Atlanta · USAmerican Red Cross · USEmory University · US

Funding

Pediatric Transfusion Medicine Academic Career AwardK07HL088922 · NHLBI · EMORY UNIVERSITY · PI JOSEPHSON, CASSANDRA D · 2007 to 2011
$594k
CENTRAL CONTROL OF THE CORONARY CIRCULATIONF32HL007001 · NHLBI · UNIVERSITY OF IOWA · PI GUTTERMAN, DAVID D. · 1985 to 1985
–
NHLBI NIH HHS HL-07-001NHLBI NIH HHS K07 HL088922
6 · The paper itself

Abstract

Granulocyte transfusions may be useful for neutropenic pediatric patients with refractory bacterial or fungal infections. Many potential adverse sequelae associated with granulocyte transfusions are well recognized, including febrile reactions, fluid overload, alloimmunization, and lung injury. Other potential adverse sequelae, however, are less well known. This case report describes an infant with familial hemophagocytic lymphohistiocytosis who developed polycythemia (hemoglobin 10-17.6 g/dl) following four daily transfusions of 20 ml/kg of apheresis collected, steroid stimulated donor granulocytes. Expanded knowledge of potential risks of transfused granulocytes will allow for rapid recognition of transfusion-related complications, should they occur.

Indexed as

FemaleGranulocytesHumansInfantInfectionsLeukocyte TransfusionLymphohistiocytosis, HemophagocyticPolycythemia

Identifiers

PMID21370438
PMCPMC3568762
OpenAlexW2001763868

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.