ArticleInternational journal of clinical pharmacy2011
Prescribing pattern of antihypertensive drugs in a general hospital in central China.
Article in International journal of clinical pharmacy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 14 citations in OpenAlex.
- Comment on: Comparison of SGLT‑2i and GLP‑1RA on cardiovascular and renal outcomes in elderly patients with T2DM: a single‑center retrospective cohort study.International urology and nephrology · 2026Article
- Management of Hypertension in the Asia-Pacific Region: A Structured Review.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2024Review
- Prescribing trend in cardiovascular patients at Ethiopian university hospital: The number of medications and implication on the clinical improvement.Pharmacology research & perspectives · 2019Article
- Systolic hypertension: an increasing clinical challenge in Asia.Hypertension research : official journal of the Japanese Society of Hypertension · 2015Review
- The healthcare burden of hypertension in Asia.Heart Asia · 2013Article
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Authors and funding
1 author at 1 institution in 1 country.
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Abstract
objectivesTo examine the prescribing pattern of antihypertensive drugs in outpatients with hypertension in a general hospital in central China and identify whether the pattern of prescribing is appropriate and in accordance with national and international guidelines for pharmacotherapy of hypertension.
settingThe internal medicine department of Zhongnan Hospital in central China.
methodAntihypertensive prescription data were collected from the hospital's central computer database from 1 March 2008 to 31 March 2008.
main outcome measureThe most frequently used antihypertensive medications, as a percentage of treatment and of monotherapy or combination therapy.
results1,206 prescriptions were included in the analysis. The mean age of the patient population was 61.3 ± 13.7 years and 68.6% were male. The mean number of drugs used by the patient was 1.45 ± 0.66. Of the patients, 62.9% were receiving monotherapy, 29.4% two drugs, 6.9% three drugs, and 0.8% four drugs. Most patients were receiving calcium channel blockers (58.0%), followed by angiotensin receptor blockers (34.2%), angiotensin-converting enzyme inhibitors (17.5%), beta-blockers (16.9%) and diuretics (16.7%).
conclusionThis study showed that most outpatients with hypertension in our hospital received monotherapy although national and international guidelines indicated that monotherapy achieves the BP target in only a limited number of hypertensive patients. We also found that the most frequently used class of antihypertensive drugs was calcium channel blockers then angiotensin receptor blockers. Despite the various benefits of diuretics, they remain underutilized. Moreover, calcium channel blockers were used most frequently in hypertensive patients with comorbidities.
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