ArticleMolecules (Basel, Switzerland)2011
Detection of cytotoxic activity of lectin on human colon adenocarcinoma (Sw480) and epithelial cervical carcinoma (C33-A).
Article in Molecules (Basel, Switzerland), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 29 citations in OpenAlex.
- Protein Fraction and Derived Peptides fromInternational journal of molecular sciences · 2026Article
- Assessment of Genotoxicity and Cytotoxicity of Tepary Bean (Life (Basel, Switzerland) · 2025Article
- Protective Role of Bee Venom (Apis mellifera) Against Kidney Damage in Female Mice with Cancer.Asian Pacific journal of cancer prevention : APJCP · 2025Article
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- Antioxidant Activity and Anticarcinogenic Effect of Extracts fromLife (Basel, Switzerland) · 2023Article
- Effect of Induced Mechanical Leaf Damage on the Yield and Content of Bioactive Molecules in Leaves and Seeds of Tepary Beans (Plants (Basel, Switzerland) · 2022Article
- Rhizoctonia bataticola lectin induces apoptosis and inhibits metastasis in ovarian cancer cells by interacting with CA 125 antigen differentially expressed on ovarian cells.Glycoconjugate journal · 2021Article
- Production, Purification, and Potential Health Applications of Edible Seeds' Bioactive Peptides: A Concise Review.Foods (Basel, Switzerland) · 2021Review
- Tepary Bean (Molecules (Basel, Switzerland) · 2020Article
- A New Galactose-Specific Lectin fromIranian journal of biotechnology · 2018Article
- Potential role of bioactive peptides in prevention and treatment of chronic diseases: a narrative review.British journal of pharmacology · 2017Review
- Cytotoxic and antiproliferative effect of tepary bean lectins on C33-A, MCF-7, SKNSH, and SW480 cell lines.Molecules (Basel, Switzerland) · 2014Article
- Effects of Tepary bean (Phaseolus acutifolius) protease inhibitor and semipure lectin fractions on cancer cells.Nutrition and cancer · 2012Article
- Article
- Purification, biochemical characterization, and bioactive properties of a lectin purified from the seeds of white tepary bean (phaseolus acutifolius variety latifolius).Molecules (Basel, Switzerland) · 2011Article
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lectins comprise a heterogeneous class of proteins that recognize the carbohydrate moieties of glycoconjugates with high specificity. Numerous studies have shown that lectins are capable of recognizing specific carbohydrate moieties displayed by malignant cells or tissues. The present work was performed to investigate the effects of tepary bean (Phaseolus acutifolius) lectins on proliferation, colony formation, and alteration of DNA synthesis of human malignant cells. Tepary bean lectin showed dose dependent effects on the inhibition of viability as well as on colony formation in two human malignant cells lines (C33-A, Sw480); By contrast, tepary bean lectin only showed significant effects on DNA synthesis on Sw480 cells. Our results provide evidence of the anti- proliferative and cytotoxic effects of the tepary bean lectins on C33-A and Sw480 cells lines.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.