ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2011
Bruchpilot, a synaptic active zone protein for anesthesia-resistant memory.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 63 citations in OpenAlex.
- Disruption of a selective vesicle pool upon retrograde amnesia dissociates memory at presynaptic terminals.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Screening for Differentially Expressed Memory Genes on a Diabetes Model Induced by High-Sugar Diet in Drosophila melanogaster: Potential Markers for Memory Deficits.Molecular neurobiology · 2024Article
- Bruchpiloting synaptic connections: Egfr in autophagy-mediated neuronal circuit development.Autophagy · 2023Article
- Anesthesia Resistant Memories in Drosophila, a Working Perspective.International journal of molecular sciences · 2022Review
- Cold Shock Disrupts Massed Training-Elicited Memory in Drosophila.International journal of molecular sciences · 2022Article
- CRY-dependent plasticity of tetrad presynaptic sites in the visual system of Drosophila at the morning peak of activity and sleep.Scientific reports · 2020Article
- Social competition stimulates cognitive performance in a sex-specific manner.Proceedings. Biological sciences · 2020Article
- CCB is Involved in Actin-Based Axonal Transport of Selected Synaptic Proteins.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Nitric oxide acts as a cotransmitter in a subset of dopaminergic neurons to diversify memory dynamics.eLife · 2019Article
- Electrical synapses between mushroom body neurons are critical for consolidated memory retrieval in Drosophila.PLoS genetics · 2019Article
- Autophagy within the mushroom body protects from synapse aging in a non-cell autonomous manner.Nature communications · 2019Article
- Mushroom Body Specific Transcriptome Analysis Reveals Dynamic Regulation of Learning and Memory Genes After Acquisition of Long-Term Courtship Memory inG3 (Bethesda, Md.) · 2018Article
- Memory enhancement by ferulic acid ester across species.Science advances · 2018Article
- TheThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Dunce Phosphodiesterase Acts as a Checkpoint for Drosophila Long-Term Memory in a Pair of Serotonergic Neurons.Neuron · 2018Article
- Drk-mediated signaling to Rho kinase is required for anesthesia-resistant memory inProceedings of the National Academy of Sciences of the United States of America · 2017Article
- Two Components of Aversive Memory inThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- The Role of Histone Deacetylase 6 in Synaptic Plasticity and Memory.Cell reports · 2017Article
- Age-associated increase of the active zone protein Bruchpilot within the honeybee mushroom body.PloS one · 2017Article
- Genetic Dissection of Aversive Associative Olfactory Learning and Memory in Drosophila Larvae.PLoS genetics · 2016Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In Drosophila, aversive associative memory of an odor consists of heterogeneous components with different stabilities. Here we report that Bruchpilot (Brp), a ubiquitous presynaptic active zone protein, is required for olfactory memory. Brp was shown before to facilitate efficient vesicle release, particularly at low stimulation frequencies. Transgenic knockdown in the Kenyon cells of the mushroom body, the second-order olfactory interneurons, revealed that Brp is required for olfactory memory. We further demonstrate that Brp in the Kenyon cells preferentially functions for anesthesia-resistant memory. Another presynaptic protein, Synapsin, was shown previously to be required selectively for the labile anesthesia-sensitive memory, which is less affected in brp knockdown. Thus, consolidated and labile components of aversive olfactory memory can be dissociated by the function of different presynaptic proteins.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.