ArticleBMC medical genetics2011
Bio-Repository of DNA in stroke (BRAINS): a study protocol.
Article in BMC medical genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Genomic risk profiling of ischemic stroke: results of an international genome-wide association meta-analysis.PloS one · 2011Pooled it
- Trial
- Multidimensional Approach of Genotype and Phenotype in Stroke Etiology: The MAGPIE Study.Health science reports · 2024Article
- Diabetes mellitus and obesity among South Asians with ischemic stroke across three countries.International journal of stroke : official journal of the International Stroke Society · 2024Article
- Ischaemic stroke in South Asians: The BRAINS study.European journal of neurology · 2023Article
- Atrial fibrillation in UK South Asian hospitalized ischemic stroke patients: The BRAINS study.PloS one · 2023Article
- Cigarette smoking as a risk factor for ischaemic stroke in young South Asian male migrants to Qatar: The BRAINS study.Qatar medical journal · 2023Article
- The Association of Coagulation Factor V (Leiden) and Factor II (Prothrombin) Mutations With Stroke.Iranian Red Crescent medical journal · 2014Article
- Bio-repository of DNA in stroke: a study protocol of three ancestral populations.JRSM cardiovascular disease · 2012Review
- Current status of stroke in Qatar: Including data from the BRAINS study.JRSM cardiovascular diseaseReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 3 countries.
Funding
Abstract
backgroundStroke is one of the commonest causes of mortality in the world and anticipated to be an increasing burden to the developing world. Stroke has a genetic basis and identifying those genes may not only help us define the mechanisms that cause stroke but also identify novel therapeutic targets. However, large scale highly phenotyped DNA repositories are required in order for this to be achieved.
methodsThe proposed Bio-Repository of DNA in Stroke (BRAINS) will recruit all subtypes of stroke as well as controls from two different continents, Europe and Asia. Subjects recruited from the UK will include stroke patients of European ancestry as well as British South Asians. Stroke subjects from South Asia will be recruited from India and Sri Lanka. South Asian cases will also have control subjects recruited. DISCUSSION: We describe a study protocol to establish a large and highly characterized stroke biobank in those of European and South Asian descent. With different ethnic populations being recruited, BRAINS has the ability to compare and contrast genetic risk factors between those of differing ancestral descent as well as those who migrate into different environments.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.