Evidence map›Paper›PMID 21366159›Full record

ReviewJournal of pediatric ophthalmology and strabismus

Computer-based image analysis for plus disease diagnosis in retinopathy of prematurity.

Leah A Wittenberg, Nina J Jonsson, R V Paul Chan, Michael F Chiang

Abstract readReview
In one paragraph

Review in Journal of pediatric ophthalmology and strabismus. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 82 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Artificial Intelligence in Retinopathy of Prematurity Diagnosis.Translational vision science & technology · 2020
    Review
  9. Article
  10. Article
  11. Telemedicine for Retinopathy of Prematurity in 2020.Journal of vitreoretinal diseases · 2019
    Article
  12. Imaging the pediatric retina - Where are we headed?Indian journal of ophthalmology · 2019
    Article
  13. Article
  14. Intravitreal bevacizumab treatment reduces ocular blood flow in retinopathy of prematurity: a four-case report.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2018
    Article
  15. Article
  16. Article
  17. Article
  18. Retinal Telemedicine.Current ophthalmology reports · 2018
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Leah A WittenbergDepartment of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
Nina J Jonsson
R V Paul Chan
Michael F Chiang
Cornell University · USOphthalmology Associates (United States) · USUniversity of British Columbia · CA

Funding

Clinical and Genetic Analysis of Retinopathy of PrematurityR01EY019474 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI CAMPBELL, JOHN PETER · 2010 to 2020
$7.0M
Mentored Vision Clinician-Scientist Program at OHSUK12EY027720 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI David Huang · 2018 to 2026
$2.2M
NEI NIH HHS EY19474NEI NIH HHS K12 EY027720NEI NIH HHS R01 EY019474
6 · The paper itself

Abstract

Presence of plus disease in retinopathy of prematurity (ROP) is an important criterion for identifying ROP requiring treatment. Plus disease is defined by a standard published photograph selected more than 20 years ago by expert consensus. However, diagnosis of plus disease has been shown to be subjective and qualitative. Computer-based image analysis using quantitative methods has potential to improve the objectivity of plus disease diagnosis. The objective was to review the published literature involving computer-based image analysis for ROP diagnosis. The PubMed and Cochrane library databases were searched for the keywords "retinopathy of prematurity" AND "image analysis" AND/OR "plus disease." Reference lists of retrieved articles were searched to identify additional relevant studies. All relevant English-language studies were reviewed. There are four main computer-based systems-ROPtool (area under the receiver operating characteristic curve [AUROC], plus tortuosity 0.95, plus dilation 0.87), RISA (AUROC, arteriolar TI 0.71, venular diameter 0.82), Vessel Map (AUROC, arteriolar dilation 0.75, venular dilation 0.96), and CAIAR (AUROC, arteriole tortuosity 0.92, venular dilation 0.91)-attempting to objectively analyze vessel tortuosity and dilation in plus disease in ROP. Some show promise for identification of plus disease using quantitative methods. This has potential to improve the diagnosis of plus disease and may contribute to the management of ROP using both traditional binocular indirect ophthalmoscopy and image-based telemedicine approaches.

Indexed as

Image Interpretation, Computer-AssistedHumansInfant, NewbornRetinal VesselsRetinopathy of Prematurity

Identifiers

PMID21366159
PMCPMC4036800
OpenAlexW2332981639

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.