ArticleMolecular vision2011
Eurasian and Sub-Saharan African mitochondrial DNA haplogroup influences pseudoexfoliation glaucoma development in Saudi patients.
Article in Molecular vision, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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Who cites it
15 citing papers in PubMed, 26 citations in OpenAlex.
- Mitochondrial Genome Study Identifies Association Between Primary Open-Angle Glaucoma and Variants inFrontiers in genetics · 2021Article
- Whole mitochondrial genome analysis in Chinese patients with keratoconus.Molecular vision · 2021Article
- Mitochondria: The Retina's Achilles' Heel in AMD.Advances in experimental medicine and biology · 2021Article
- Increased Plasma Levels of 8-Hydroxy-2'-deoxyguanosine (8-OHdG) in Patients with Pseudoexfoliation Glaucoma.Journal of ophthalmology · 2019Article
- Elevated levels of plasma tumor necrosis factor alpha in patients with pseudoexfoliation glaucoma.Clinical ophthalmology (Auckland, N.Z.) · 2018Article
- Genotypic diversity of the Killer Cell Immunoglobulin-like Receptors (KIR) and their HLA class I Ligands in a Saudi population.Genetics and molecular biology · 2016Article
- Association of total antioxidants level with glaucoma type and severity.Saudi medical journal · 2015Article
- Mitochondrial DNA haplogroups confer differences in risk for age-related macular degeneration: a case control study.BMC medical genetics · 2013Article
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- Lack of association of SNP rs4236601 near CAV1 and CAV2 with POAG in a Saudi cohort.Molecular vision · 2012Article
- Susceptibility to primary angle closure glaucoma in Saudi Arabia: the possible role of mitochondrial DNA ancestry informative haplogroups.Molecular vision · 2011Article
- Mitochondrial disorders and the eye.Eye and brain · 2011Review
- Decreased total antioxidants status in the plasma of patients with pseudoexfoliation glaucoma.Molecular vision · 2011Article
- Mitochondrial DNA lineages of African origin confer susceptibility to primary open-angle glaucoma in Saudi patients.Molecular vision · 2011Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate whether different mitochondrial DNA (mtDNA) haplogroups have a role on the development of pseudoexfoliation glaucoma (PEG) in the Saudi Arab population.
methodsThe mtDNA regulatory region and coding regions comprising mtDNA haplogroup diagnostic polymorphisms were sequenced in patients with PEG (n=94), healthy matched controls (free of PEG; n=112) and a healthy Saudi Arab population group (n=810).
resultsThe Eurasian haplogroup T and the Sub-Saharan African Haplogroup L2 confer susceptibility to PEG, whereas the Eurasian haplogroup N1 was associated with reduced risk to develop PEG in the Saudi Arab population.
conclusionsMitochondrial haplogroups T and L2 may play a role in the development of PEG in the Saudi Arabian population.
Indexed as
Identifiers
21364909PMC3044700W2154437995What OpenQuestion holds
Registered trials
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