ArticleBritish journal of cancer2011
Population-based mammography screening below age 50: balancing radiation-induced vs prevented breast cancer deaths.
Article in British journal of cancer, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 50 citations in OpenAlex.
- XGBoost Enhances the Performance of SAFE: A Novel Microwave Imaging System for Early Detection of Malignant Breast Cancer.Cancers · 2025Article
- Cost-effectiveness of Breast Cancer Screening With Magnetic Resonance Imaging for Women at Familial Risk.JAMA oncology · 2020Article
- A Validation Study of a Multiple Reaction Monitoring-Based Proteomic Assay to Diagnose Breast Cancer.Journal of breast cancer · 2019Article
- Diagnostic imaging in pregnancy: Making informed decisions.Obstetric medicine · 2019Review
- State of the evidence 2017: an update on the connection between breast cancer and the environment.Environmental health : a global access science source · 2017Review
- [Screening for cervical and breast cancer].Der Pathologe · 2016Review
- Is the false-positive rate in mammography in North America too high?The British journal of radiology · 2016Review
- Is the Linear No-Threshold Dose-Response Paradigm Still Necessary for the Assessment of Health Effects of Low Dose Radiation?Journal of Korean medical science · 2016Review
- Breast Cancer Induced by X-Ray Mammography Screening? A Review Based on Recent Understanding of Low-Dose Radiobiology.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2016Article
- Principles of Cancer Screening.The Surgical clinics of North America · 2015Review
- Tipping the balance of benefits and harms to favor screening mammography starting at age 40 years: a comparative modeling study of risk.Annals of internal medicine · 2012Article
- The manner in which calories are restricted impacts mammary tumor cancer prevention.Journal of carcinogenesis · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionExposure to ionizing radiation at mammography screening may cause breast cancer. Because the radiation risk increases with lower exposure age, advancing the lower age limit may affect the balance between screening benefits and risks. The present study explores the benefit-risk ratio of screening before age 50.
methodsThe benefits of biennial mammography screening, starting at various ages between 40 and 50, and continuing up to age 74 were examined using micro-simulation. In contrast with previous studies that commonly used excess relative risk models, we assessed the radiation risks using the latest BEIR-VII excess absolute rate exposure-risk model.
resultsThe estimated radiation risk is lower than previously assessed. At a mean glandular dose of 1.3 mGy per view that was recently measured in the Netherlands, biennial mammography screening between age 50 and 74 was predicted to induce 1.6 breast cancer deaths per 100,000 women aged 0-100 (range 1.3-6.3 extra deaths at a glandular dose of 1-5 mGy per view), against 1121 avoided deaths in this population. Advancing the lower age limit for screening to include women aged 40-74 was predicted to induce 3.7 breast cancer deaths per 100,000 women aged 0-100 (range 2.9-14.4) at biennial screening, but would also prevent 1302 deaths.
conclusionThe benefits of mammography screening between age 40 and 74 were predicted to outweigh the radiation risks.
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