Evidence map›Paper›PMID 21362740›Full record

SynthesisThe American journal of psychiatry2011

Interpersonal psychotherapy for depression: a meta-analysis.

Pim Cuijpers, Anna S Geraedts, Patricia van Oppen, Gerhard Andersson, John C Markowitz, Annemieke van Straten

Erratum issued Registry-linked trialOpen access · greenAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in The American journal of psychiatry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT04356274 (Participatory System Dynamics vs Audit and Feedback), which is not on this map. Cited by 140 papers, 23 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
140citing papers in PubMed, 23 pooled it
39.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04356274 naenrolling by invitationnot on this mapstarted 2019, after this paper: background citation

Participatory System Dynamics vs Audit and Feedback: A Cluster Randomized Trial of Mechanisms of Implementation Change to Expand Reach of Evidence-based Addiction and Mental Health Care

TypeinterventionalSponsorPalo Alto Veterans Institute for ResearchRan2019 to 2027Enrolled720ConditionsPTSD, Depression, Alcohol Use Disorder, Opioid Use DisorderArmsParticipatory System Dynamics (PSD), Audit and Feedback (AF)
3 · Its place in the literature

Who cites it

140 citing papers in PubMed, 23 syntheses or guidelines pooled it, 499 citations in OpenAlex.

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  4. The Empirical Status of Mindfulness-Based Interventions: A Systematic Review of 44 Meta-Analyses of Randomized Controlled Trials.Perspectives on psychological science : a journal of the Association for Psychological Science · 2022
    Pooled it
  5. Listening Visits for maternal depression: a meta-analysis.Archives of women's mental health · 2021
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  7. Interpersonal Psychotherapy to Reduce Psychological Distress in Perinatal Women: A Systematic Review.International journal of environmental research and public health · 2020
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80 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Pim CuijpersDepartment of Clinical Psychology, Vrije Universiteit Amsterdam, the Netherlands. p.cuijpers@psy.vu.nl
Anna S Geraedts
Patricia van Oppen
Gerhard Andersson
John C Markowitz
Annemieke van Straten
Columbia University · USUniversity Medical Center · USKarolinska Institutet · SENew York State Psychiatric Institute

Funding

Psychotherapies for Chronic Posttraumatic Stress DisorderR01MH079078 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MARKOWITZ, JOHN C · 2008 to 2012
$3.1M
NIMH NIH HHS R01 MH079078
6 · The paper itself

Abstract

objectiveInterpersonal psychotherapy (IPT), a structured and time-limited therapy, has been studied in many controlled trials. Numerous practice guidelines have recommended IPT as a treatment of choice for unipolar depressive disorders. The authors conducted a meta-analysis to integrate research on the effects of IPT.

methodThe authors searched bibliographical databases for randomized controlled trials comparing IPT with no treatment, usual care, other psychological treatments, and pharmacotherapy as well as studies comparing combination treatment using pharmacotherapy and IPT. Maintenance studies were also included.

resultsThirty-eight studies including 4,356 patients met all inclusion criteria. The overall effect size (Cohen's d) of the 16 studies that compared IPT and a control group was 0.63 (95% confidence interval [CI]=0.36 to 0.90), corresponding to a number needed to treat of 2.91. Ten studies comparing IPT and other psychological treatments showed a nonsignificant differential effect size of 0.04 (95% CI=-0.14 to 0.21; number needed to treat=45.45) favoring IPT. Pharmacotherapy (after removal of one outlier) was more effective than IPT (d=-0.19, 95% CI=-0.38 to -0.01; number needed to treat=9.43), and combination treatment was not more effective than IPT alone, although the paucity of studies precluded drawing definite conclusions. Combination maintenance treatment with pharmacotherapy and IPT was more effective in preventing relapse than pharmacotherapy alone (odds ratio=0.37; 95% CI=0.19 to 0.73; number needed to treat=7.63).

conclusionsThere is no doubt that IPT efficaciously treats depression, both as an independent treatment and in combination with pharmacotherapy. IPT deserves its place in treatment guidelines as one of the most empirically validated treatments for depression.

Indexed as

Interpersonal RelationsCombined Modality TherapyDepressive DisorderHumansPsychotherapyTreatment Outcome

Identifiers

PMID21362740
PMCPMC3646065
OpenAlexW2016616105

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.