Evidence map›Paper›PMID 21362519›Full record

ArticleSeminars in oncology2011

Current and future clinical applications for optical imaging of cancer: from intraoperative surgical guidance to cancer screening.

Costas G Hadjipanayis, Huabei Jiang, David W Roberts, Lily Yang

Abstract read
In one paragraph

Article in Seminars in oncology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Costas G HadjipanayisDepartment of Neurosurgery, Emory University School of Medicine, Atlanta, GA 30322, USA. chadjip@emory.edu
Huabei Jiang
David W Roberts
Lily Yang

Funding

Tissue and Animal UseU54CA119338 · NCI · EMORY UNIVERSITY · PI NIE, SHUMING · 2005 to 2009
$18.4M
Coregistered Fluorescence-Enhanced Resection of Malignant GliomaR01NS052274 · NINDS · DARTMOUTH-HITCHCOCK CLINIC · PI ROBERTS, DAVID W · 2007 to 2018
$4.6M
Targeted Therapy of Triple Negative Breast Cancer Using Theranostic NanoparticlesR01CA154129 · NCI · EMORY UNIVERSITY · PI YANG, LILY · 2011 to 2015
$1.7M
Targeted Nanoprobes For Intraoperative optical Imaging of Breast Cancer MarginsR01CA133722 · NCI · EMORY UNIVERSITY · PI YANG, LILY · 2008 to 2012
$1.6M
X-ray/Fluorescence Molecular and Diffuse Optical Tomography of GliomaK25CA138578 · NCI · DARTMOUTH COLLEGE · PI LEBLOND, FREDERIC · 2009 to 2012
$722k
HSV-Mediated Chemoradiosensitivity Human Glioma ModelK08NS053454 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HADJIPANAYIS, CONSTANTINOS GEORGE · 2006 to 2010
$670k
NCI NIH HHS K25 CA138578NCI NIH HHS K25CA138578NCI NIH HHS R01 CA133722NCI NIH HHS R01 CA154129NCI NIH HHS U54 CA119338NINDS NIH HHS K08 NS053454NINDS NIH HHS R01 NS052274NINDS NIH HHS R01NS052274-01
6 · The paper itself

Abstract

Optical imaging is an inexpensive, fast, and sensitive imaging approach for the noninvasive detection of human cancers in locations that are accessible by an optical imaging device. Light is used to probe cellular and molecular function in the context of cancer in the living body. Recent advances in the development of optical instrumentation make it possible to detect optical signals produced at a tissue depth of several centimeters. The optical signals can be endogenous contrasts that capture the heterogeneity and biological status of different tissues, including tumors, or extrinsic optical contrasts that selectively accumulate in tumors to be imaged after local or systemic delivery. The use of optical imaging is now being applied in the clinic and operating room for the localization and resection of malignant tumors in addition to screening for cancer.

Indexed as

Fluorescent DyesTomography, OpticalBrain NeoplasmsBreast NeoplasmsContrast MediaFemaleHumansMolecular ImagingMolecular ProbesNanoparticlesNeoplasmsSurgery, Computer-AssistedContrast MediaFluorescent DyesMolecular Probes

Identifiers

PMID21362519
PMCPMC3061227

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.