Evidence map›Paper›PMID 21362512›Full record

ReviewSeminars in oncology2011

The evolution of imaging in cancer: current state and future challenges.

Luke J Higgins, Martin G Pomper

Abstract readReview
In one paragraph

Review in Seminars in oncology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Radiolabeled bombesin derivatives for preclinical oncological imaging.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2017
    Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. GCPII imaging and cancer.Current medicinal chemistry · 2012
    Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Luke J HigginsRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.
Martin G Pomper
Johns Hopkins University · US

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI Rosalie Wollett · 1985 to 2026
$208.6M
Translational Applications of mda-7/IL-24 in CancerP01CA104177 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI FISHER, PAUL B · 2005 to 2009
$6.5M
PSMA-based Cancer Imaging AgentsR01CA134675 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI POMPER, MARTIN G · 2009 to 2025
$6.2M
MDA-7: Novel Cancer Therapeutic GeneR01CA097318 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI FISHER, PAUL B · 2002 to 2012
$2.8M
Small Animal Imaging Resource (SAIR)U24CA092871 · NCI · JOHNS HOPKINS UNIVERSITY · PI POMPER, MARTIN G · 2007 to 2011
$2.3M
Pancreatic Cancer Management by Novel Gene Therapy & Dietary AgentsR01CA127641 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI FISHER, PAUL B · 2009 to 2012
$1.2M
Screening strategy for small molecules inhibitors of cancerR03MH093195 · NIMH · VIRGINIA COMMONWEALTH UNIVERSITY · PI FISHER, PAUL B · 2011 to 2012
$75k
NCI NIH HHS P01 CA104177NCI NIH HHS P30 CA006973NCI NIH HHS R01 CA097318NCI NIH HHS R01 CA127641NCI NIH HHS R01 CA134675NCI NIH HHS U24 CA092871NIMH NIH HHS R03 MH093195
6 · The paper itself

Abstract

Molecular imaging allows for the remote, noninvasive sensing and measurement of cellular and molecular processes in living subjects. Drawing upon a variety of modalities, molecular imaging provides a window into the biology of cancer from the subcellular level to the patient undergoing a new, experimental therapy. As signal transduction cascades and protein interaction networks become clarified, an increasing number of relevant targets for cancer therapy--and imaging--become available. Although conventional imaging is already critical to the management of patients with cancer, molecular imaging will provide even more relevant information, such as early detection of changes with therapy, identification of patient-specific cellular and metabolic abnormalities, and the disposition of therapeutic, gene-tagged cells throughout the body--all of which will have a considerable impact on morbidity and mortality. This overview discusses molecular imaging in oncology, providing examples from a variety of modalities, with an emphasis on emerging techniques for translational imaging.

Indexed as

Antineoplastic AgentsGene Expression ProfilingGenetic TherapyHumansMaleMolecular ImagingMolecular Targeted TherapyNeoplasmsProstatic NeoplasmsTranslational Research, BiomedicalAntineoplastic Agents

Identifiers

PMID21362512
PMCPMC4313866
OpenAlexW2108500150

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.