Evidence map›Paper›PMID 21361677›Full record

ArticleJournal of biomedical optics2011

Improving sensitivity in nonlinear Raman microspectroscopy imaging and sensing.

Rajan Arora, Georgi I Petrov, Jian Liu, Vladislav V Yakovlev

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Detecting anthrax in the mail by coherent Raman microspectroscopy.Proceedings of the National Academy of Sciences of the United States of America · 2012
    Article
  8. Article
  9. Coherent anti-Stokes Raman scattering microspectroscopy: an emerging technique for non-invasive optical assessment of a local bio-nano-environment.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rajan AroraUniversity of Wisconsin - Milwaukee, Department of Physics, 1900 E. Kenwood Boulevard, Milwaukee, Wisconsin 53211, USA.
Georgi I Petrov
Jian Liu
Vladislav V Yakovlev

Funding

High-throughput vibrational cytometryR21EB011703 · NIBIB · UNIVERSITY OF WISCONSIN MILWAUKEE · PI YAKOVLEV, VLADISLAV V. · 2010 to 2011
$396k
Microspectroscopy of aging effects in RPE melanosomesR15EY020805 · NEI · UNIVERSITY OF WISCONSIN MILWAUKEE · PI KUCHIN, SERGEI V · 2010 to 2010
$362k
NEI NIH HHS R15 EY020805NIBIB NIH HHS R21 EB011703NIBIB NIH HHS R21EB011703
6 · The paper itself

Abstract

Nonlinear Raman microspectroscopy based on a broadband coherent anti-Stokes Raman scattering is an emerging technique for noninvasive, chemically specific, microscopic analysis of tissues and large population of cells and particles. The sensitivity of this imaging is a critical aspect of a number of the proposed biomedical application. It is shown that the incident laser power is the major parameter controlling this sensitivity. By careful optimizing the laser system, the high-quality vibrational spectra acquisition at the multi-kHz rate becomes feasible.

Indexed as

LasersBiosensing TechniquesComputer-Aided DesignEquipment DesignEquipment Failure AnalysisImage EnhancementMicroscopyNonlinear DynamicsReproducibility of ResultsSensitivity and SpecificitySpectrum Analysis, Raman

Identifiers

PMID21361677
PMCPMC3061330

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.