Evidence map›Paper›PMID 21360749›Full record

ArticleMagnetic resonance in medicine2011

Ultrashort TE MR imaging of bovine cortical bone: the effect of water loss on the T1 and T2* relaxation times.

Nima Kokabi, Won Bae, Eric Diaz, Christine B Chung, Graeme M Bydder, Jiang Du

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Micron-resolution Imaging of Cortical Bone under 14 T Ultrahigh Magnetic Field.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  2. Investigation of the Longitudinal Relaxation Time of Rat Tibial Cortical Bone Using SWIFT.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2017
    Article
  3. Quantitative ultrashort echo time (UTE) MRI of human cortical bone: correlation with porosity and biomechanical properties.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2012
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nima KokabiDepartment of Radiology, University of California, San Diego, California 92103-8226, USA.
Won Bae
Eric Diaz
Christine B Chung
Graeme M Bydder
Jiang Du

Funding

UTE MR Imaging of the Cartilaginous Endplate in the Lumbar SpineK01AR059764 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BAE, WON C · 2010 to 2013
$469k
NIAMS NIH HHS K01 AR059764
6 · The paper itself

Abstract

The effects of water loss on the T1 and T2* of bovine cortical bone were investigated using ultrashort echo time sequences with signals excited either by a short hard pulse or by two longer half pulses. Nine bovine femur samples were prepared and sequentially air- and oven-dried. On average 3.42% of bone by weight was lost after air-drying for 3 days, with another 5.98% of bone weight loss after oven-drying at 100°C for 24 h. T1 and T2* were measured after every 1% decrease in weight, with 9-10% bone weight loss at the termination of the drying process. After both forms of drying, the overall T1 decreased 33% from 153±18 ms to 102±17 ms when measured using the hard pulse and from 186±25 ms to 122±23 ms when using the half pulses. T2* decreased by 45-50% from 368±29 μs to 201±19 μs using the hard pulse and from 379±35 μs to 191±17 μs using the half pulses. A steady decrease of 26-31% was observed in both T1 and T2* with the first 3-4% bone water loss after air-drying. Oven-drying at 100°C for 24 h resulted on an additional 4% T1 reduction but 25% T2* reduction.

Indexed as

AlgorithmsAnimalsBody WaterCattleFemurImage Interpretation, Computer-AssistedMagnetic Resonance ImagingReproducibility of ResultsSensitivity and Specificity

Identifiers

PMID21360749
PMCPMC4682560

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.