Evidence map›Paper›PMID 21360283›Full record

Trial reportJournal of behavioral medicine2011

Changes in spirituality partly explain health-related quality of life outcomes after Mindfulness-Based Stress Reduction.

Jeffrey M Greeson, Daniel M Webber, Moria J Smoski, Jeffrey G Brantley, Andrew G Ekblad, Edward C Suarez, Ruth Quillian Wolever

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Journal of behavioral medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00887614 (Mechanisms of Mindfulness), which is not on this map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00887614 nacompletednot on this map

Mechanisms of Mindfulness: Effects on Sleep Quality, Stress Physiology and CVD Risk

TypeinterventionalSponsorDuke UniversityRan2009 to 2010Enrolled372ConditionsStress, Psychological, SleepArmsMindfulness-Based Stress Reduction (MBSR)
3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Effect of mindfulness-based therapy on spiritual well-being in breast cancer patients: a randomized controlled study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Trial
  3. Trial
  4. How does yoga reduce stress? A clinical trial testing psychological mechanisms.Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Trial
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  12. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeffrey M GreesonDuke Integrative Medicine, Duke University Medical Center, Durham, NC 27710, USA. jeffrey.greeson@duke.edu
Daniel M Webber
Moria J Smoski
Jeffrey G Brantley
Andrew G Ekblad
Edward C Suarez
Ruth Quillian Wolever

Funding

Emotion Regulation in Late-Life Depression: Effectiveness and Neural MechanismsK23MH087754 · NIMH · DUKE UNIVERSITY · PI SMOSKI, MORIA J. · 2009 to 2013
$684k
Mechanisms of Mindfulness: Effects on Sleep Quality, Stress Physiology & CVD RiskK99AT004945 · NCCIH · DUKE UNIVERSITY · PI GREESON, JEFFREY M · 2008 to 2009
$178k
NCCIH NIH HHS K99 AT004945NCCIH NIH HHS K99AT004945NIMH NIH HHS K23 MH087754NIMH NIH HHS K23MH087754
6 · The paper itself

Abstract

Mindfulness-Based Stress Reduction is a secular behavioral medicine program that has roots in meditative spiritual practices. Thus, spirituality may partly explain Mindfulness-Based Stress Reduction outcomes. Participants (N = 279; M (SD) age = 45(12); 75% women) completed an online survey before and after an 8-week Mindfulness-Based Stress Reduction program. Structural equation modeling was used to test the hypothesis that, following Mindfulness-Based Stress Reduction, the relationship between enhanced mindfulness and improved health-related quality of life is mediated by increased daily spiritual experiences. Changes in both spirituality and mindfulness were significantly related to improvement in mental health. Although the initial mediation hypothesis was not supported, an alternate model suggested that enhanced mindfulness partly mediated the association between increased daily spiritual experiences and improved mental health-related quality of life (indirect effect: β = 0.07, P = 0.017). Effects on physical health-related quality of life were not significant. Findings suggest a novel mechanism by which increased daily spiritual experiences following Mindfulness-Based Stress Reduction may partially explain improved mental health as a function of greater mindfulness.

Indexed as

SpiritualityAdultAgedFemaleHealth SurveysHumansMaleMeditationMiddle AgedModels, PsychologicalQuality of LifeStress, Psychological

Identifiers

PMID21360283
PMCPMC3151546

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.