ArticleMicrobial ecology2011
Secondary metabolites of Pseudomonas fluorescens CHA0 drive complex non-trophic interactions with bacterivorous nematodes.
Article in Microbial ecology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 72 citations in OpenAlex.
- Evaluation of Pseudomonas fluorescens for biocontrol of early blight (Alternaria solani) in tomato in North Wollo, Ethiopia.PloS one · 2026Article
- Meloidogyne incognita parasitism is affected by Pseudomonas protegens CHA0 and its effects on tomato-associated microbiota.Environmental microbiome · 2025Article
- Behavioral adaptations ofPeerJ · 2025Review
- Article
- Metabolites limiting predator growth wane with prey biodiversity.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Nonribosomal peptides protectChemical science · 2023Article
- Interaction between nematodes and bacteria enhances soil carbon sequestration under organic material amendments.Frontiers in microbiology · 2023Article
- Polyyne-producingFrontiers in microbiology · 2023Article
- Combining in vitro and in vivo screening to identify efficient Pseudomonas biocontrol strains against the phytopathogenic bacterium Ralstonia solanacearum.MicrobiologyOpen · 2022Article
- Identifying the Compounds of the Metabolic Elicitors ofPlants (Basel, Switzerland) · 2020Article
- GC-MS analysis of volatile organic compounds from Bambara groundnut rhizobacteria and their antibacterial properties.World journal of microbiology & biotechnology · 2019Article
- Cyanide Production bymBio · 2017Article
- Antimicrobial and Insecticidal: Cyclic Lipopeptides and Hydrogen Cyanide Produced by Plant-BeneficialFrontiers in microbiology · 2017Article
- Rhizobacteria with nematicide aptitude: enzymes and compounds associated.World journal of microbiology & biotechnology · 2016Review
- Insect pathogenicity in plant-beneficial pseudomonads: phylogenetic distribution and comparative genomics.The ISME journal · 2016Article
- Comparative genomic and functional analyses: unearthing the diversity and specificity of nematicidal factors in Pseudomonas putida strain 1A00316.Scientific reports · 2016Article
- Assessment of DAPG-producing Pseudomonas fluorescens for Management of Meloidogyne incognita and Fusarium oxysporum on Watermelon.Journal of nematology · 2016Article
- Controlling the Microbiome: Microhabitat Adjustments for Successful Biocontrol Strategies in Soil and Human Gut.Frontiers in microbiology · 2016Article
- Article
- Microbiology, genomics, and clinical significance of the Pseudomonas fluorescens species complex, an unappreciated colonizer of humans.Clinical microbiology reviews · 2014Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-trophic interactions are increasingly recognised as a key parameter of predator-prey interactions. In soil, predation by bacterivorous nematodes is a major selective pressure shaping soil bacterial communities, and many bacteria have evolved defence mechanisms such as toxicity. In this study, we show that extracellular secondary metabolites produced by the model soil bacterium Pseudomonas fluorescens CHA0 function as a complex defence strategy against bacterivorous nematodes. Using a collection of functional mutants lacking genes for the biosynthesis of one or several extracellular metabolites, we evaluated the impact of bacterial secondary metabolites on the survival and chemotactic behaviour of the nematode Caenorhabditis elegans. Additionally, we followed up the stress status of the nematodes by measuring the activation of the abnormal DAuer Formation (DAF) stress cascade. All studied secondary metabolites contributed to the toxicity of the bacteria, with hydrogen cyanide efficiently repelling the nematodes, and both hydrogen cyanide and 2,4-DAPG functioning as nematicides. Moreover, these metabolites elicited the DAF stress response cascade of C. elegans, showing that they affect nematode physiology already at sublethal concentrations. The results suggest that bacterial secondary metabolites responsible for the suppression of plant pathogens strongly inhibit bacterivorous nematodes and thus likely contribute to the resistance of bacteria against predators in soil.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.