ArticleParasitology research2011
Free-living amoebae as vectors of cryptosporidia.
Article in Parasitology research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A history of over 40 years of potentially pathogenic free-living amoeba studies in Brazil - a systematic review.Memorias do Instituto Oswaldo Cruz · 2022Pooled it
- Interactions between free-living amoebae and Cryptosporidium parvum: an experimental study.Parasite (Paris, France) · 2023Article
- Cryptosporidiosis: From Prevention to Treatment, a Narrative Review.Microorganisms · 2022Review
- Epidemiology of free-living amoebae in the Philippines: a review and update.Pathogens and global health · 2022Review
- Free-Living Amoebas in Extreme Environments: The True Survival in our Planet.BioMed research international · 2022Review
- War of the microbial world: Acanthamoeba spp. interactions with microorganisms.Folia microbiologica · 2021Review
- Contact lens-related polymicrobial keratitis: Acanthamoeba spp. genotype T4 and Candida albicans.Parasitology research · 2018Article
- Free-Living Amoebae as Hosts for and Vectors of Intracellular Microorganisms with Public Health Significance.Viruses · 2017Review
- Relevance of free-living amoebae as hosts for phylogenetically diverse microorganisms.Parasitology research · 2014Review
- The first genotype determination of Acanthamoeba potential threat to human health, isolated from natural water reservoirs in Poland.Parasitology research · 2014Article
- Incidence and molecular diversity of Acanthamoeba species isolated from public baths in Hungary.Parasitology research · 2014Article
- First report of an Acanthamoeba genotype T13 isolate as etiological agent of a keratitis in humans.Parasitology research · 2014Article
- Cytotoxic effect of organic solvents and surfactant agents on Acanthamoeba castellanii cysts.Parasitology research · 2014Article
- Isolation and characterization of Acanthamoeba strains from soil samples in Gran Canaria, Canary Islands, Spain.Parasitology research · 2014Article
- Inactivation of exogenous endoparasite stages by chemical disinfectants: current state and perspectives.Parasitology research · 2013Review
- Prevalence of Acanthamoeba spp. (Sarcomastigophora: Acanthamoebidae) in wild populations of Aedes aegypti (Diptera: Culicidae).Parasitology research · 2012Article
- Functional expression and characterization of an iron-containing superoxide dismutase of Acanthamoeba castellanii.Parasitology research · 2012Article
- Acanthamoeba spp. as vehicle and reservoir of adenoviruses.Parasitology research · 2012Article
- Isolation of Acanthamoeba species in surface waters of Gilan province-north of Iran.Parasitology research · 2012Article
Corrections and comments
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Authors and funding
2 authors.
Funding
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Abstract
In the present article, the study to examine the ability of free-living amoebae (FLA) to serve as vectors of cryptosporidia is presented. Ten strains of different free-living amoebae of the FLA collection of the Parasitology Lab at Koblenz were cultivated in the presence of Cryptosporidium parvum oocysts. After phagocytosis and ingestion, the oocysts could be found in food vacuoles within the cytoplasm of the trophozoites of two different FLA strains. The uptake and the transport of the oocysts within the trophozoites could be demonstrated in an Acanthamoeba sp. (group II) strain (maximum, three oocysts; average, one oocyst) as well as in a Thecamoeba quadrilineata strain (maximum, 15 oocysts; average, eight oocysts), with the help of light microscopy. We found that these free-living amoebae can temporarily harbour cryptosporidia, thus supporting the suggestion that FLA may act as carriers and vehicles for cryptosporidia. However, proliferation did not take place within the host amoebae. No cryptosporidium oocysts were found within the cysts of the amoebae. To our knowledge, this is the first study to determine the "host range" of free-living amoebae as vectors and vehicles of cryptosporidia. Free-living amoebae appear able to act as carriers or vectors of the oocysts and thus may play a certain role in the transmission of cryptosporidia.
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Registered trials
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