ReviewCurrent gastroenterology reports2011
Evaluation of patients with suspected laryngopharyngeal reflux: a practical approach.
Review in Current gastroenterology reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Association of Heterotopic Gastric Mucosa in the Upper Esophagus (HGMUE) with Pharyngolaryngeal Symptoms: A Systematic Review and Meta-Analysis.Digestive diseases and sciences · 2024Pooled it
- Change in Symptoms and Mucosal Findings after Proton Pump Inhibitor in Patients with Laryngopharyngeal Reflux.International archives of otorhinolaryngology · 2025Article
- Laryngopharyngeal reflux: is laparoscopic fundoplication an effective treatment?Annals of the Royal College of Surgeons of England · 2022Review
- Reflux-related Extraesophageal Symptoms Until Proven Otherwise: A Direct Measurement of Abnormal Proximal Exposure Based on Hypopharyngeal Multichannel Intraluminal Impedance as a Reliable Indicator for Successful Treatment Outcomes.Journal of neurogastroenterology and motility · 2022Article
- Usefulness of matrix metalloproteinase-7 in saliva as a diagnostic biomarker for laryngopharyngeal reflux disease.Scientific reports · 2021Article
- Laryngopharyngeal Reflux Among Patients Undergoing Bariatric Surgery.Obesity surgery · 2021Article
- The Effects of Empiric Antireflux Treatment on Laryngopharyngeal and Gastroesophageal Reflux Disease.Sisli Etfal Hastanesi tip bulteni · 2020Article
- Pepsin promotes IL-8 signaling-induced epithelial-mesenchymal transition in laryngeal carcinoma.Cancer cell international · 2019Article
- Depression, Hematologic Parameters, and Blood Levels of Vitamin BClinical medicine insights. Ear, nose and throat · 2019Article
- Laryngopharyngeal Reflux Disease - LPRD.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2017Article
- Upper aerodigestive tract disorders and gastro-oesophageal reflux disease.World journal of clinical cases · 2015Review
- Laryngopharyngeal reflux: diagnosis, treatment, and latest research.International archives of otorhinolaryngology · 2014Review
- Extra-esophageal manifestations of gastroesophageal reflux disease: diagnosis and treatment.Drugs · 2013Review
- Extra-esophageal manifestations of GERD: who responds to GERD therapy?Current gastroenterology reports · 2013Review
- New tests for the evaluation of laryngopharyngeal reflux.Gastroenterology & hepatology · 2013Article
- Risk factors for laryngopharyngeal reflux.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2012Article
- Sympathetic Nerve Entrapment Point Injection as an Antireflux Procedure for Refractory Laryngopharyngeal Reflux: A First Case Report of Innovative Autonomic Regulation.Innovations in clinical neuroscienceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Laryngopharyngeal reflux (LPR) is associated with symptoms of laryngeal irritation such as throat pain, cough, and voice change. Currently, the two main diagnostic tools are laryngoscopy and reflux monitoring. On laryngoscopy, the signs most commonly used to diagnose LPR are erythema and edema of the larynx; however, these signs are not specific for LPR, may be associated with other causes, and may even be found in healthy individuals. In addition, pH testing has low sensitivity in diagnosing gastroesophageal reflux disease-related laryngeal findings. Proton pump inhibitor (PPI) therapy remains the cornerstone of treatment. The current management recommendation for this group of patients is empiric therapy with twice-daily PPIs for 1 to 2 months. In the majority of those who are unresponsive to such therapy, other causes of laryngeal irritation are considered. Surgical fundoplication is most effective in those who are responsive to acid-suppressive therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.