SynthesisArchives of orthopaedic and trauma surgery2011
Mortality and morbidity associated with simultaneous bilateral or staged bilateral total knee arthroplasty: a meta-analysis.
Synthesis in Archives of orthopaedic and trauma surgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.
- Consensus statement from the consensus conference on bilateral total knee arthroplasty group.Clinical orthopaedics and related research · 2013Guideline
- Two-surgeon simultaneous bilateral total knee arthroplasty does not provide poor prosthetic alignment : A prospective randomized controlled study.Der Orthopade · 2022Trial
- Safety of one-stage bilateral total knee arthroplasty -one surgeon sequential vs. two surgeons simultaneous: a randomized controlled study.International orthopaedics · 2020Trial
- Simultaneous bilateral total knee arthroplasty lowers reoperation and cost at the expense of higher complications and mortality: a meta-analysis and systematic review.Knee surgery & related research · 2025Review
- [Effectiveness and safety analysis of simultaneous bilateral total knee arthroplasty in treatment of patients aged 65 years and younger with bilateral knee osteoarthritis].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025Article
- Optimal timing for the second surgery in staged bilateral total knee arthroplasty: a patient-determined interval approach.BMC surgery · 2025Article
- High Pain Self-Efficacy Reduces the Use of Analgesics in the Early Postoperative Period After Total Knee Arthroplasty: A Retrospective Cohort Study.Journal of pain research · 2025Article
- Simultaneous total hip and knee arthroplasties in hemophilic arthropathy: series of 5 cases.Acta orthopaedica et traumatologica turcica · 2024Article
- Evolution and Hotspots in Bilateral Total Joint Arthroplasty Research: A Bibliometric Analysis.Clinics in orthopedic surgery · 2024Review
- Mortality Rates in Staged Bilateral Total Knee Arthroplasty: A Systematic Review and Meta-Analysis.Cureus · 2024Review
- Bilateral Total Knee Arthroplasty (TKA) in a One-Stage Procedure Versus Two-Stage Procedure: A Retrospective Study.Healthcare (Basel, Switzerland) · 2024Article
- Emergency-Driven Multiple Simultaneous Invasive Procedures in Haemophilia.Life (Basel, Switzerland) · 2024Article
- Article
- Subsequent total joint arthroplasty: Are we learning from the first stage?World journal of orthopedics · 2024Article
- Bilateral simultaneous knee arthroplasty shows comparable early outcome and complication rate as staged bilateral knee arthroplasty for patients scored ASA 1-3 if performed by a high-volume surgeon: a retrospective cohort study of 127 cases.Archives of orthopaedic and trauma surgery · 2024Article
- Staging Bilateral Total Knee Arthroplasties Reduces Alignment Outliers.The Journal of arthroplasty · 2022Article
- Staged Bilateral Total Knee Arthroplasty: When Should the Second Knee be Replaced?The archives of bone and joint surgery · 2021Review
- One-stage bilateral unicompartmental knee arthroplasty is a suitable option vs. the two-stage approach: a meta-analysis.EFORT open reviews · 2021Review
- A reproducible method for biochemical, histological and functional assessment of the effects of ischaemia-reperfusion syndrome in the lower limbs.Scientific reports · 2021Article
- Obesity and its effect on outcomes in same-day bilateral total knee arthroplasty.Annals of translational medicine · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the mortality and postoperative morbidity associated with simultaneous bilateral or staged bilateral total knee arthroplasty (TKA).
methodsWe identified eligible studies in PubMed (1980-2010), OVID MEDLINE (1980-2010) and the Cochrane library. Data were extracted and evaluated by two reviewers independently. Data analyses were conducted with Stata 10.0.
resultsFourteen studies met our inclusion criteria. Combined results showed that the prevalence of mortality [OR = 3.202, 95% CI (1.852-5.537)], mortality at 30 days postoperatively [OR = 5.564, 95% CI (2.392-12.939)] and neurological complications [OR = 2.906, 95% CI (1.200-7.037)] were significantly higher in the population who had undergone simultaneous TKA compared with those who had undergone staged TKA. The prevalence of infection, pulmonary embolism, deep-vein thrombosis, and cardiac complications between the two populations was not significantly different.
conclusionCompared with staged bilateral TKA, simultaneous bilateral TKA might carry a higher potential risk of postoperative complications. Patients should be aware of this information when deciding whether to proceed with simultaneous bilateral TKA. The poor quality of the studies calls into question the robustness of the analyses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.